← Back to patent-cliff list
CAS 79-31-2
2-Methylpropionic acid
Codes：Ceftazidime-025
Application context (from source-drug indications)
膀胱炎阿维巴坦钠/头孢他啶胆囊炎阿维巴坦钠/头孢他啶腹膜炎阿维巴坦钠/头孢他啶腹腔感染阿维巴坦钠/头孢他啶肝脓肿阿维巴坦钠/头孢他啶脓毒病阿维巴坦钠/头孢他啶细菌感染头孢他啶/他唑巴坦钠呼吸道感染头孢他啶/他唑巴坦钠泌尿系统感染头孢他啶/他唑巴坦钠
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 阿维巴坦钠/头孢他啶Avibactam Sodium/Ceftazidime | Tier C — Watch / trade | - |
| 头孢他啶/他唑巴坦钠Ceftazidime/Tazobactam Sodium | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-Methylpropionic acid→2-Bromo-2-methylpropanoic acid→t-Butyl 2-bromo isobutyrate→2(Z)-(2-Aminothiazol-4-yl)-2-(hydroxyimino)acetic acid ethyl ester→tert-Butyl 2-([(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-ethoxy-2-oxoethylidene]amino]oxy)-2-methylpropanoate→(2Z)-(2-Amino-1,3-thiazol-4-yl)[[(1-tert-butoxy-2-methyl-1-oxopropan-2-yl)oxy]imino]acetic acid→2-([[(1Z)-1-(2-Amino-1,3-thiazol-4-yl)-2-chloro-2-oxoethylidene]amino]oxy)-2-methylpropanoic acid hydrochloride→(6R,7R)-7-Amino-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydroiodide
2-Methylpropionic acid→2-Bromo-2-methylpropanoic acid→t-Butyl 2-bromo isobutyrate→2(Z)-(2-Aminothiazol-4-yl)-2-(hydroxyimino)acetic acid ethyl ester→tert-Butyl 2-([(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-ethoxy-2-oxoethylidene]amino]oxy)-2-methylpropanoate→(2Z)-(2-Amino-1,3-thiazol-4-yl)[[(1-tert-butoxy-2-methyl-1-oxopropan-2-yl)oxy]imino]acetic acid→2-([[(1Z)-1-(2-Amino-1,3-thiazol-4-yl)-2-chloro-2-oxoethylidene]amino]oxy)-2-methylpropanoic acid hydrochloride→(6R,7R)-7-Amino-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydroiodide
Intermediates available on this site
No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.