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CAS 79902-31-1

(4R,6R)-4-[[tert-Butyl(dimethyl)silyl]oxy]-6-[2-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl]oxan-2-one

Codes:(I)122234-5-a

Application context (from source-drug indications)

血脂障碍非诺贝特/辛伐他汀高脂血症非诺贝特/辛伐他汀心脏和血管疾病非诺贝特/辛伐他汀高胆固醇血症非诺贝特/辛伐他汀

Source drugs (routes using this intermediate)

DrugTierExpiry
非诺贝特/辛伐他汀Fenofibrate/SimvastatinTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

非诺贝特/辛伐他汀优化路线steps: 2total yield: /
(4R,6R)-4-[[tert-Butyl(dimethyl)silyl]oxy]-6-[2-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl]oxan-2-one→2,2-dimethylbutanoic acid→(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-[[tert-Butyl(dimethyl)silyl]oxy]-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate

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