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CAS 820217-06-9

Bromo(2,4,6-tricyclohexylphenyl)magnesium

Codes:(XI)270899-2-b

Application context (from source-drug indications)

重度抑郁症盐酸艾司氯胺酮自杀意念盐酸艾司氯胺酮抑郁症盐酸艾司氯胺酮麻醉盐酸艾司氯胺酮难治性抑郁症盐酸艾司氯胺酮疼痛盐酸艾司氯胺酮

Source drugs (routes using this intermediate)

DrugTierExpiry
盐酸艾司氯胺酮Esketamine HydrochlorideTier B — Position early2029

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

盐酸艾司氯胺酮优化路线steps: 2total yield: /
(aR)-3,3'-Diiodo-2,2'-bis(methoxymethoxy)-6,6'-dioctyl-1,1'-binaphthalene→Bromo(2,4,6-tricyclohexylphenyl)magnesium→(aR)-6,6'-Dioctyl-3,3'-bis(2,4,6-tricyclohexylphenyl)-1,1'-binaphthalene-2,2'-diol

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