CAS 836-59-9

4-(2-(4-bromophenoxy)ethyl)morpholine

Codes: KX-01-008

Application context (from source-drug indications)

Actinic keratosisTirbanibulin角化病TirbanibulinBasal cell carcinomaTirbanibulinObesityTirbanibulinInsulin resistanceTirbanibulinPsoriasisTirbanibulin

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
Tirbanibulin	Tier C — Watch / trade	-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

TirbanibulinOptimised routesteps: 5total yield: 60.16 g

4-(2-chloroethyl)morpholine→4-bromophenol→4-(2-(4-bromophenoxy)ethyl)morpholine→(6-fluoropyridin-3-yl)boronic acid→4-(2-(4-(6-fluoropyridin-3-yl)phenoxy)ethyl)morpholine→2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)acetonitrile→methyl 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)acetate

Intermediates available on this site

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