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CAS 851528-79-5
(R)-2-(4-((2-ethoxy-3-(4-(trifluoromethyl)phenoxy)propyl)thio)-2-methylphenoxy)acetic acid
Codes: SELALD-007
Application context (from source-drug indications)
Biliary cirrhosisSeladelpar lysine dihydrateSclerosing cholangitisSeladelpar lysine dihydrateLiver cirrhosisSeladelpar lysine dihydrateHepatic function declineSeladelpar lysine dihydrateFibrosisSeladelpar lysine dihydrateNon-alcoholic steatohepatitisSeladelpar lysine dihydrate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Seladelpar lysine dihydrate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
4-(trifluoromethyl)phenol→(R)-oxiran-2-ylmethanol→(S)-2-((4-(trifluoromethyl)phenoxy)methyl)oxirane→ethyl 2-(4-mercapto-2-methylphenoxy)acetate→ethyl (R)-2-(4-((2-hydroxy-3-(4-(trifluoromethyl)phenoxy)propyl)thio)-2-methylphenoxy)acetate→ethyl (R)-2-(4-((2-ethoxy-3-(4-(trifluoromethyl)phenoxy)propyl)thio)-2-methylphenoxy)acetate→(R)-2-(4-((2-ethoxy-3-(4-(trifluoromethyl)phenoxy)propyl)thio)-2-methylphenoxy)acetic acid→ethyl 2-(o-tolyloxy)acetate→ethyl 2-(4-(chlorosulfonyl)-2-methylphenoxy)acetate→(R)-2-(4-((2-ethoxy-3-(4-(trifluoromethyl)phenoxy)propyl)thio)-2-methylphenoxy)acetic acid compound with (S)-2,6-diaminohexanoic acid (1:1)
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