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CAS 855473-48-2
methyl (R,E)-2-(3-(acetylthio)-3-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)propyl)benzoate
Codes: MONT-023
Application context (from source-drug indications)
Allergic rhinitisMontelukastAsthmaMontelukastHypersensitivity reactionMontelukastSeasonal allergic rhinitisMontelukastPerennial allergic rhinitisMontelukastExercise-induced asthmaMontelukast
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Montelukast | Tier B — Position early | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(R,E)-2-(1-(((1-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)thio)methyl)cyclopropyl)acetic acid→methyl (R,E)-2-(3-(acetylthio)-3-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)propyl)benzoate→(R,E)-2-(2-(3-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-mercaptopropyl)phenyl)propan-2-ol ((4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate→methyl 2-(1-(bromomethyl)cyclopropyl)acetate→methyl (R,E)-2-(1-(((1-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)thio)methyl)cyclopropyl)acetate→diisobutylamine 2-(1-((((R)-1-(3-((E)-2-((E)-6-(2-chloroethylidene)-5,6-dihydropyridin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)thio)methyl)cyclopropyl)acetate
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