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CAS 86073-42-9
N-[(2R)-1-(4-Methoxyphenyl)propan-2-yl]acetamide
Codes：Tamsulosin Hydrochloride-049
Application context (from source-drug indications)
勃起功能障碍他达拉非/坦洛新前列腺增生他达拉非/坦洛新下尿路症状琥珀酸索利那新/盐酸坦洛新前列腺增生琥珀酸索利那新/盐酸坦洛新膀胱过度活动症琥珀酸索利那新/盐酸坦洛新药物相关的副作用和不良反应琥珀酸索利那新/盐酸坦洛新膀胱颈梗阻琥珀酸索利那新/盐酸坦洛新前列腺增生度他雄胺/盐酸坦洛新
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 他达拉非/坦洛新Tadalafil/Tamsulosin | Tier C — Watch / trade | - |
| 琥珀酸索利那新/盐酸坦洛新Solifenacin Succinate/Tamsulosin Hydrochloride | Tier C — Watch / trade | - |
| 度他雄胺/盐酸坦洛新Dutasteride/Tamsulosin Hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(-)-alpha-Amino-p-hydroxyhydrocinnamic acid→N-Acetyl-L-tyrosine→Ethyl N-acetyl-L-tyrosinate→Ethyl N-acetyl-O-methyl-L-tyrosinate→N-[(2S)-1-Hydroxy-3-(4-methoxyphenyl)propan-2-yl]acetamide→N-[(2R)-1-(4-Methoxyphenyl)propan-2-yl]acetamide→1-Methoxy-4-[(1E)-2-nitroprop-1-en-1-yl]benzene→N-Hydroxy-1-(4-methoxyphenyl)propan-2-imine→N-[(1E)-1-(4-Methoxyphenyl)prop-1-en-2-yl]acetamide→N-[(2R)-1-(4-Methoxy-3-sulfamoylphenyl)propan-2-yl]acetamide→5-(2(R)-Aminopropyl)-2-methoxybenzenesulfonamide→2-(2-Ethoxyphenoxy)ethyl 4-methylbenzenesulfonate→(-)-5-[2(R)-[2-(2-Ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide→1-Hydroxy-2-ethoxybenzene→1-Chloro-2-hydroxyethane→2-(2-Ethoxyphenoxy)ethanol
(4-Methoxyphenyl)acetic acid→1-(4-Methoxyphenyl)-2-propanone→1,1-Diphenylmethylamine→(2R)-N-(Diphenylmethyl)-1-(4-methoxyphenyl)propan-2-amine→(-)-2-(4-Methoxyphenyl)-1-methylethanamine→N-[(2R)-1-(4-Methoxyphenyl)propan-2-yl]acetamide→(+)-2,2'-Dihydroxy-1,1'-dinaphthyl→(aR)-5,5',6,6',7,7',8,8'-Octahydro[1,1'-binaphthalene]-2,2'-diol→(aR)-4-Chloro-8,9,10,11,12,13,14,15-octahydro-4H-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine→3,5-Dimethylpiperidine→3,5-Dimethylpyridine
(-)-alpha-Amino-p-hydroxyhydrocinnamic acid→N-Acetyl-L-tyrosine→Ethyl N-acetyl-L-tyrosinate→Ethyl N-acetyl-O-methyl-L-tyrosinate→N-[(2S)-1-Hydroxy-3-(4-methoxyphenyl)propan-2-yl]acetamide→N-[(2R)-1-(4-Methoxyphenyl)propan-2-yl]acetamide→1-Methoxy-4-[(1E)-2-nitroprop-1-en-1-yl]benzene→N-Hydroxy-1-(4-methoxyphenyl)propan-2-imine→N-[(1E)-1-(4-Methoxyphenyl)prop-1-en-2-yl]acetamide→N-[(2R)-1-(4-Methoxy-3-sulfamoylphenyl)propan-2-yl]acetamide→5-(2(R)-Aminopropyl)-2-methoxybenzenesulfonamide→2-(2-Ethoxyphenoxy)ethyl 4-methylbenzenesulfonate→(-)-5-[2(R)-[2-(2-Ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide→1-Hydroxy-2-ethoxybenzene→1-Chloro-2-hydroxyethane→2-(2-Ethoxyphenoxy)ethanol
(4-Methoxyphenyl)acetic acid→1-(4-Methoxyphenyl)-2-propanone→1,1-Diphenylmethylamine→(2R)-N-(Diphenylmethyl)-1-(4-methoxyphenyl)propan-2-amine→(-)-2-(4-Methoxyphenyl)-1-methylethanamine→N-[(2R)-1-(4-Methoxyphenyl)propan-2-yl]acetamide→(+)-2,2'-Dihydroxy-1,1'-dinaphthyl→(aR)-5,5',6,6',7,7',8,8'-Octahydro[1,1'-binaphthalene]-2,2'-diol→(aR)-4-Chloro-8,9,10,11,12,13,14,15-octahydro-4H-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine→3,5-Dimethylpiperidine→3,5-Dimethylpyridine
(-)-alpha-Amino-p-hydroxyhydrocinnamic acid→N-Acetyl-L-tyrosine→Ethyl N-acetyl-L-tyrosinate→Ethyl N-acetyl-O-methyl-L-tyrosinate→N-[(2S)-1-Hydroxy-3-(4-methoxyphenyl)propan-2-yl]acetamide→N-[(2R)-1-(4-Methoxyphenyl)propan-2-yl]acetamide→1-Methoxy-4-[(1E)-2-nitroprop-1-en-1-yl]benzene→N-Hydroxy-1-(4-methoxyphenyl)propan-2-imine→N-[(1E)-1-(4-Methoxyphenyl)prop-1-en-2-yl]acetamide→N-[(2R)-1-(4-Methoxy-3-sulfamoylphenyl)propan-2-yl]acetamide→5-(2(R)-Aminopropyl)-2-methoxybenzenesulfonamide→2-(2-Ethoxyphenoxy)ethyl 4-methylbenzenesulfonate→(-)-5-[2(R)-[2-(2-Ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide→1-Hydroxy-2-ethoxybenzene→1-Chloro-2-hydroxyethane→2-(2-Ethoxyphenoxy)ethanol
(4-Methoxyphenyl)acetic acid→1-(4-Methoxyphenyl)-2-propanone→1,1-Diphenylmethylamine→(2R)-N-(Diphenylmethyl)-1-(4-methoxyphenyl)propan-2-amine→(-)-2-(4-Methoxyphenyl)-1-methylethanamine→N-[(2R)-1-(4-Methoxyphenyl)propan-2-yl]acetamide→(+)-2,2'-Dihydroxy-1,1'-dinaphthyl→(aR)-5,5',6,6',7,7',8,8'-Octahydro[1,1'-binaphthalene]-2,2'-diol→(aR)-4-Chloro-8,9,10,11,12,13,14,15-octahydro-4H-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine→3,5-Dimethylpiperidine→3,5-Dimethylpyridine
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