CAS 88-65-3

2-Bromobenzoic acid

Codes: Tolfenamic Acid-005

Application context (from source-drug indications)

ArthritisTolfenamic AcidMigraineTolfenamic AcidPainTolfenamic AcidDysmenorrhoeaTolfenamic Acid进行性核上性麻痹Tolfenamic Acid

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
Tolfenamic Acid	Tier C — Watch / trade	-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Tolfenamic AcidOptimised routesteps: 4total yield: 215g(Tolfenamic Acid (Free))

2-Chlorobenzoic acid→Sodium 2-chlorobenzoate→2-Chlorobenoic acid potassium salt→2-Amino-6-chlorotoluene→2-Bromobenzoic acid→2-Bromobenzoic acid potassium salt

Tolfenamic AcidOptimised routesteps: 1total yield: 92g(Tolfenamic Acid (Free))

2-Amino-6-chlorotoluene→2-Chlorobenzoic acid→2-Bromobenzoic acid→2-Iodobenzoic acid

Intermediates available on this site

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