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CAS 90719-32-7

(S)-4-benzyloxazolidin-2-one

Codes: ABAC-011

Application context (from source-drug indications)

HIV infectionAbacavir Sulfate艾滋病痴呆综合征Abacavir Sulfate

Source drugs (routes using this intermediate)

DrugTierExpiry
Abacavir SulfateTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Abacavir SulfateOptimised routesteps: 7total yield: 27.00 mg
(S)-4-benzyloxazolidin-2-one→pent-4-enoic pivalic anhydride→(S)-4-benzyl-3-(pent-4-enoyl)oxazolidin-2-one→(S)-3-((2S,3R)-2-allyl-3-methylpent-4-enoyl)-4-benzyloxazolidin-2-one→ABAC-015→(S)-4-benzyl-3-((1R,2R)-2-hydroxycyclopentanecarbonyl)oxazolidin-2-one→(1R,5R)-5-(hydroxymethyl)cyclopent-2-enol→((1R,2R)-2-acetoxycyclopent-3-en-1-yl)methyl acetate→N6-cyclopropyl-9H-purine-2,6-diamine→((1S,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methyl acetate

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