CAS 923035-06-7

3-[1-(Methylamino)ethyl]phenol

Codes: (III)145089-4-a, (IV)145089-17-a

Application context (from source-drug indications)

Alzheimer's diseaseRivastigmine TartrateDementiaRivastigmine TartrateParkinson's diseaseRivastigmine Tartrate抗胆碱能综合征Rivastigmine Tartrate神经行为学表现Rivastigmine TartrateCognitive impairmentRivastigmine Tartrate

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
Rivastigmine Tartrate	Tier B — Position early	-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Rivastigmine TartrateOptimised routesteps: 5total yield: /

1-(3-Hydroxyphenyl)ethanone→Aminomethane→3-[1-(Methylamino)ethyl]phenol→3-[1-(Dimethylamino)ethyl]phenol→3-(1-Aminoethyl)phenol→(-)-3-((1S)-1-(Dimethylamino)ethyl)phenol→N-Ethyl-N-methylcarbamic chloride→Ethyl(methyl)carbamic bromide→(S)-3-(1-(Dimethylamino)ethyl)phenyl ethyl(methyl)carbamate

Rivastigmine TartrateOptimised routesteps: 4total yield: /

1-(3-Hydroxyphenyl)ethanone→Aminomethane→3-[(1E)-N-Methylethanimidoyl]phenol→3-[1-(Methylamino)ethyl]phenol→3-[1(S)-(Methylamino)ethyl]phenol→(-)-3-((1S)-1-(Dimethylamino)ethyl)phenol

Intermediates available on this site

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