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CAS 937273-34-2
N-(3-((allyloxy)methyl)-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-4-(3-((allyloxy)methyl)phenyl)pyrimidin-2-amine
Codes: PACR-016
Application context (from source-drug indications)
MyelofibrosisPacritinib CitrateThrombocytopeniaPacritinib CitrateAcute myeloid leukaemiaPacritinib CitrateEssential thrombocythaemiaPacritinib CitratePolycythaemia veraPacritinib CitrateChronic myelomonocytic leukaemiaPacritinib Citrate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Pacritinib Citrate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-((allyloxy)methyl)-1-(2-chloroethoxy)-4-nitrobenzene→4-(3-((allyloxy)methyl)phenyl)-2-chloropyrimidine→pyrrolidine→1-(2-(2-((allyloxy)methyl)-4-nitrophenoxy)ethyl)pyrrolidine→3-((allyloxy)methyl)-4-(2-(pyrrolidin-1-yl)ethoxy)aniline→N-(3-((allyloxy)methyl)-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-4-(3-((allyloxy)methyl)phenyl)pyrimidin-2-amine
Intermediates available on this site
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