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CAS 95609-48-6

5-(3,4-Dichlorophenyl)oxolan-2-one

Codes:Sertraline Hydrochloride-059

Application context (from source-drug indications)

强迫性障碍枸橼酸舍曲林

Source drugs (routes using this intermediate)

DrugTierExpiry
枸橼酸舍曲林Sertraline CitrateTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

枸橼酸舍曲林优化路线steps: 6total yield: 22.5g(Sertraline Hydrochloride (API))
1,2-Dichlorobenzene→2,5-Dioxotetrahydrofuran→4-(3,4-Dichlorophenyl)-4-oxobutanoic acid→5-(3,4-Dichlorophenyl)oxolan-2-one→Benzene→4-(3,4-Dichlorophenyl)-1-tetralone→N-[(1E)-4-(3,4-Dichlorophenyl)-3,4-dihydronaphthalen-1(2H)-ylidene]methanamine→(±)-cis-4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine→(±)-cis-4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine hydrogen chloride

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