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CAS 99199-60-7
6-fluorochromane-2-carboxylic acid
Codes: NEBI-002
Application context (from source-drug indications)
HypertensionNebivolol HydrochlorideEssential hypertensionNebivolol Hydrochloride糖尿病周围神经病变Nebivolol HydrochlorideBreast cancerNebivolol HydrochloridePeripheral arterial diseaseNebivolol HydrochlorideDiabetesNebivolol Hydrochloride
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Nebivolol Hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
6-fluoro-4-oxo-4H-chromene-2-carboxylic acid→6-fluorochromane-2-carboxylic acid→ethyl 6-fluorochromane-2-carboxylate→(6-fluorochroman-2-yl)methanol→6-fluorochromane-2-carbaldehyde→6-fluoro-2-(oxiran-2-yl)chromane→2-(benzylamino)-1-(6-fluorochroman-2-yl)ethan-1-ol→2,2'-(benzylazanediyl)bis(1-(6-fluorochroman-2-yl)ethan-1-ol)
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Unibest Nantong cGMP Site | (±)-(R*, R* und R*, S*)-6-Fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran Pharmaceutical Intermediates | On request | On request | On request | — | |
| Unibest Taizhou GMP-like Site | (2S, 2’S)-6-Fluoro-2-(2’-oxiranyl)chromane Pharmaceutical Intermediates | On request | On request | On request | — | |
| Qualified Partner — East China API Works | (+)-(S,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran Pharmaceutical Intermediates | On request | On request | On request | — | |
| Unibest Nantong cGMP Site | (R)-6-Fluoro-2-[(R)-2-oxiranyl]chromane Pharmaceutical Intermediates | On request | On request | On request | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.