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CAS 1202265-63-1
N-isobutyl-1-(4-methoxybutyl)-N-((3S,5R)-5-(morpholine-4-carbonyl)piperidin-3-yl)-1H-benzo[d]imidazole-2-carboxamide
登记编号：Imarikiren
应用背景（按来源药适应症）
高血压Imarikiren hydrochloride糖尿病肾病Imarikiren hydrochloride肝功能衰退Imarikiren hydrochloride肾功能不全Imarikiren hydrochloride
来源药（使用该中间体的合成路线）
| 品种 | 梯队 | 到期年 |
|---|---|---|
| Imarikiren hydrochloride | Tier C · 观察 / 贸易 | - |
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
pyridine-3,5-dicarboxylic acid→dimethyl pyridine-3,5-dicarboxylate→1-(tert-butyl) 3,5-dimethyl piperidine-1,3,5-tricarboxylate→1-(tert-butoxycarbonyl)-5-(methoxycarbonyl)piperidine-3-carboxylic acid→(3S,5R)-1-(tert-butoxycarbonyl)-5-(methoxycarbonyl)piperidine-3-carboxylic acid→1-(tert-butyl) 3-methyl (3R,5S)-5-isocyanatopiperidine-1,3-dicarboxylate→1-(tert-butyl) 3-methyl (3R,5S)-5-(((benzyloxy)carbonyl)amino)piperidine-1,3-dicarboxylate→1-(tert-butyl) 3-methyl (3R,5S)-5-aminopiperidine-1,3-dicarboxylate→1-(tert-butyl) 3-methyl (3R,5S)-5-(isobutylamino)piperidine-1,3-dicarboxylate→2-(trichloromethyl)-1H-benzo[d]imidazole→1-(tert-butyl) 3-methyl (3R,5S)-5-(N-isobutyl-1H-benzo[d]imidazole-2-carboxamido)piperidine-1,3-dicarboxylate→4-methoxybutyl methanesulfonate→1-(tert-butyl) 3-methyl (3R,5S)-5-(N-isobutyl-1-(4-methoxybutyl)-1H-benzo[d]imidazole-2-carboxamido)piperidine-1,3-dicarboxylate→(3R,5S)-1-(tert-butoxycarbonyl)-5-(N-isobutyl-1-(4-methoxybutyl)-1H-benzo[d]imidazole-2-carboxamido)piperidine-3-carboxylic acid→tert-butyl (3S,5R)-3-(N-isobutyl-1-(4-methoxybutyl)-1H-benzo[d]imidazole-2-carboxamido)-5-(morpholine-4-carbonyl)piperidine-1-carboxylate→N-isobutyl-1-(4-methoxybutyl)-N-((3S,5R)-5-(morpholine-4-carbonyl)piperidin-3-yl)-1H-benzo[d]imidazole-2-carboxamide→N-isobutyl-1-(4-methoxybutyl)-N-((3S,5R)-5-(morpholine-4-carbonyl)piperidin-3-yl)-1H-benzo[d]imidazole-2-carboxamide hydrochloride
pyridine-3,5-dicarboxylic acid→dimethyl pyridine-3,5-dicarboxylate→(3S,5R)-1-(tert-butoxycarbonyl)-5-(methoxycarbonyl)piperidine-3-carboxylic acid→1-(tert-butyl) 3-methyl (3R,5S)-5-isocyanatopiperidine-1,3-dicarboxylate→1-(tert-butyl) 3-methyl (3R,5S)-5-(((benzyloxy)carbonyl)amino)piperidine-1,3-dicarboxylate→tert-butyl (3S,5R)-3-(N-isobutyl-1-(4-methoxybutyl)-1H-benzo[d]imidazole-2-carboxamido)-5-(morpholine-4-carbonyl)piperidine-1-carboxylate→1-(tert-butoxycarbonyl)piperidine-3,5-dicarboxylic acid→tert-butyl (1S,5S)-2,4-dioxo-3-oxa-7-azabicyclo[3.3.1]nonane-7-carboxylate→(R)-1-phenylethan-1-amine (3S,5R)-1-(tert-butoxycarbonyl)-5-(methoxycarbonyl)piperidine-3-carboxylate→(3R,5S)-5-(((benzyloxy)carbonyl)amino)-1-(tert-butoxycarbonyl)piperidine-3-carboxylic acid→tert-butyl (3S,5R)-3-(((benzyloxy)carbonyl)amino)-5-(morpholine-4-carbonyl)piperidine-1-carboxylate→tert-butyl (3S,5R)-3-(isobutylamino)-5-(morpholine-4-carbonyl)piperidine-1-carboxylate succinate→1-(4-methoxybutyl)-2-(trichloromethyl)-1H-benzo[d]imidazole→2-nitroaniline→1-chloro-4-methoxybutane→N-(4-methoxybutyl)-2-nitroaniline→N1-(4-methoxybutyl)benzene-1,2-diamine→methyl 2,2,2-trichloroacetimidate→N-isobutyl-1-(4-methoxybutyl)-N-((3S,5R)-5-(morpholine-4-carbonyl)piperidin-3-yl)-1H-benzo[d]imidazole-2-carboxamide→N-isobutyl-1-(4-methoxybutyl)-N-((3S,5R)-5-(morpholine-4-carbonyl)piperidin-3-yl)-1H-benzo[d]imidazole-2-carboxamide hydrochloride
本站可供应的对应中间体
目录暂未收录该靶点的在售中间体 —— 可直接发起询价，需求会进入撮合池。
本页为中间体 CAS 注册档案：同 CAS 的多条路线登记已合并；后续供应商报价与买方需求以该 CAS 为主键撮合。