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CAS 1247119-83-0
2-(4-ethylphenyl)-2-methylpropanoic acid
登记编号：ALEC-016
应用背景（按来源药适应症）
非小细胞肺癌阿来替尼盐酸盐肺癌阿来替尼盐酸盐
来源药（使用该中间体的合成路线）
| 品种 | 梯队 | 到期年 |
|---|---|---|
| 阿来替尼盐酸盐Alectinib Hydrochloride | Tier B · 提前布局 | 2030 |
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
4-(piperidin-4-yl)morpholine→2-(4-bromophenyl)-2-methylpropanoic acid→potassium trifluoro(vinyl)borate→2-methyl-2-(4-vinylphenyl)propanoic acid→2-(4-ethylphenyl)-2-methylpropanoic acid→2-(4-ethyl-3-iodophenyl)-2-methylpropanoic acid→3-(tert-butoxy)-3-oxopropanoic acid→tert-butyl 4-(4-ethyl-3-iodophenyl)-4-methyl-3-oxopentanoate→4-chloro-3-nitrobenzonitrile→tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate→tert-butyl 6-cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylate hydrochloride→6-cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylic acid
本站可供应的对应中间体
同 CAS 多家在售供应横向对比；价格区间为供应方挂牌口径，实价以询价确认为准。
| 供应商 | 产品 | 价格区间 | 最小起订 | 货期 | 资质 |
|---|---|---|---|---|---|
| Qualified Partner — East China API Works | 2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Nantong cGMP Site | tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Taizhou GMP-like Site | tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan -2-yl)-1Hindole-3-carboxylate Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Qualified Partner — East China API Works | tert-butyl 4-(4-ethyl-3-iodophenyl)-4-methyl-3-oxopentanoate Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Nantong cGMP Site | 4-(piperidin-4-yl)morpholine Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
本页为中间体 CAS 注册档案：同 CAS 的多条路线登记已合并；后续供应商报价与买方需求以该 CAS 为主键撮合。