← 返回专利悬崖列表
CAS 1423719-37-2
4-Methylbenzene-1-sulfonic acid 5-chloro-2-(piperidin-4-yl)pyrimidine
登记编号：(XIIIb)805433-1-a,(XIIIb)805433-1-b
应用背景（按来源药适应症）
特发性肺纤维化那米司特间质性肺疾病那米司特肺纤维化那米司特肌炎那米司特系统性硬皮病那米司特肌病那米司特
来源药（使用该中间体的合成路线）
| 品种 | 梯队 | 到期年 |
|---|---|---|
| 那米司特Nerandomilast | Tier C · 观察 / 贸易 | - |
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
2-Mercaptoacetic acid methyl ester→2-Propenoic acid methyl ester→3-(Methoxycarbonylmethylthio)propionsauremethylester→2-Carbomethoxy-2,3,4,5-tetrahydrothiophen-3-one→Carbamide→3-Ureido-4,5-dihydro-thiophene-2-carboxylic acid methyl ester→6,7-Dihydrothieno[3,2-d]pyrimidine-2,4-diol→2,4-Dichloro-6,7-dihydrothieno[3,2-d]pyrimidine→(1-Aminocyclobutyl)methanol tosylate→(1-Aminocyclobutyl)methanol hydrogen chloride→1-Aminocyclobutanecarboxylic acid hydrochloride→[1-[(2-Chloro-6,7-dihydrothieno[3,2-d]pyrimidin-4-yl)amino]cyclobutyl]methanol→(5R)-2-Chloro-4-[[1-(hydroxymethyl)cyclobutyl]amino]-6,7-dihydro-5H-5lambda4-thieno[3,2-d]pyrimidin-5-one→5-Chloro-2-(piperidin-4-yl)pyrimidine hydrogen chloride→4-Methylbenzene-1-sulfonic acid 5-chloro-2-(piperidin-4-yl)pyrimidine→5-Chloro-2-(piperidin-4-yl)pyrimidine sulfate→4-(5-Chloropyrimidin-2-yl)piperidin-1-ium hexafluoridophosphate(1-)→Piperidine-4-carboximidamide
5-Chloro-2-(piperidin-4-yl)pyrimidine hydrogen chloride→4-Methylbenzene-1-sulfonic acid 5-chloro-2-(piperidin-4-yl)pyrimidine→5-Chloro-2-(piperidin-4-yl)pyrimidine sulfate→4-(5-Chloropyrimidin-2-yl)piperidin-1-ium hexafluoridophosphate(1-)→2,4,5-Trichloropyrimidine→4-Piperidinecarbonitrile→Methyl piperidine-4-carboximidate hydrogen chloride→Piperidine-4-carboximidamide→Piperidine-4-carboximidamide hydrogen chloride→2-Chloro-1,3-bis(dimentylamino)trimethinium hexafluorophosphate→2,5-Dichloropyrimidine→5-Chloro-2-iodopyrimidine→(1-tert-Butoxycarbonyl-1,2,3,6-tetrahydropyridin-4-yl)boronic acid pinacol ester→Boc-4-(5-chloropyrimidin-2-yl)-3,6-dihydropyridine→Boc-4-(5-chloropyrimidin-2-yl)piperidine
本站可供应的对应中间体
目录暂未收录该靶点的在售中间体 —— 可直接发起询价，需求会进入撮合池。
本页为中间体 CAS 注册档案：同 CAS 的多条路线登记已合并；后续供应商报价与买方需求以该 CAS 为主键撮合。