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CAS 1434126-87-0
1-(tert-butyl) 3-ethyl (3S,4S)-4-methylpyrrolidine-1,3-dicarboxylate
登记编号：IMR-687-005
应用背景（按来源药适应症）
收缩性心力衰竭Tovinontrine舒张期心力衰竭Tovinontrine心脏病Tovinontrine心脏衰竭Tovinontrine镰状细胞血症Tovinontrineβ-地中海贫血Tovinontrine
来源药（使用该中间体的合成路线）
| 品种 | 梯队 | 到期年 |
|---|---|---|
| Tovinontrine | Tier C · 观察 / 贸易 | - |
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
N-benzyl-1-methoxy-N-((trimethylsilyl)methyl)methanamine→ethyl (E)-but-2-enoate→ethyl 1-benzyl-4-methylpyrrolidine-3-carboxylate→ethyl (3S,4S)-1-benzyl-4-methylpyrrolidine-3-carboxylate→1-(tert-butyl) 3-ethyl (3S,4S)-4-methylpyrrolidine-1,3-dicarboxylate→(3S,4S)-1-(tert-butoxycarbonyl)-4-methylpyrrolidine-3-carboxylic acid→tert-butyl (3S,4S)-3-(methoxy(methyl)carbamoyl)-4-methylpyrrolidine-1-carboxylate→tert-butyl (3S,4S)-3-acetyl-4-methylpyrrolidine-1-carboxylate→tert-butyl (3S,4S)-3-(2-bromoacetyl)-4-methylpyrrolidine-1-carboxylate→methyl 2,4-dibromo-1H-imidazole-5-carboxylate→methyl 2,4-dibromo-1-(2-((3S,4S)-1-(tert-butoxycarbonyl)-4-methylpyrrolidin-3-yl)-2-oxoethyl)-1H-imidazole-5-carboxylate→ert-butyl (3S,4S)-3-(1,3-dibromo-8-oxo-7,8-dihydroimidazo[1,5-a]pyrazin-6-yl)-4-methylpyrrolidine-1-carboxylate→2-(3,6-dihydro-2H-pyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane→tert-butyl (3S,4S)-3-(1-bromo-3-(3,6-dihydro-2H-pyran-4-yl)-8-oxo-7,8-dihydroimidazo[1,5-a]pyrazin-6-yl)-4-methylpyrrolidine-1-carboxylate→tert-butyl (3S,4S)-3-methyl-4-(8-oxo-3-(tetrahydro-2H-pyran-4-yl)-7,8-dihydroimidazo[1,5-a]pyrazin-6-yl)pyrrolidine-1-carboxylate→6-((3S,4S)-4-methylpyrrolidin-3-yl)-3-(tetrahydro-2H-pyran-4-yl)imidazo[1,5-a]pyrazin-8(7H)-one hydrochloride→2-(chloromethyl)pyrimidine→1H-imidazole-5-carboxylic acid→methyl 1H-imidazole-5-carboxylate
本站可供应的对应中间体
目录暂未收录该靶点的在售中间体 —— 可直接发起询价，需求会进入撮合池。
本页为中间体 CAS 注册档案：同 CAS 的多条路线登记已合并；后续供应商报价与买方需求以该 CAS 为主键撮合。