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CAS 24405-35-4
ethyl (2Z)-2-[(2-chlorophenyl)methylidene]-3-oxobutanoate
登记编号：(III)109067-9-a
应用背景（按来源药适应症）
高血压Olmesartan Medoxomil/Amlodipine orotate原发性高血压缬沙坦/氨氯地平乳清酸盐
来源药（使用该中间体的合成路线）
| 品种 | 梯队 | 到期年 |
|---|---|---|
| Olmesartan Medoxomil/Amlodipine orotateOlmesartan Medoxomil/Amlodipine orotate | Tier C · 观察 / 贸易 | - |
| 缬沙坦/氨氯地平乳清酸盐Valsartan/Amlodipine Orotate | Tier C · 观察 / 贸易 | - |
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
2-Butynoic acid methyl ester→1-Phenylmethylamine→ethyl (2Z)-2-[(2-chlorophenyl)methylidene]-3-oxobutanoate→3-methyl 5-propyl 1-benzyl-4-(2-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate→3-ethyl 5-methyl 4-(2-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate→3-ethyl 5-methyl 2-(bromomethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate→2-azidoethan-1-ol→3-methyl 5-propyl 6-[(2-azidoethoxy)methyl]-4-(2-chlorophenyl)-2-methyl-1,4-dihydropyridine-3,5-dicarboxylate
2-Butynoic acid methyl ester→1-Phenylmethylamine→ethyl (2Z)-2-[(2-chlorophenyl)methylidene]-3-oxobutanoate→3-methyl 5-propyl 1-benzyl-4-(2-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate→3-ethyl 5-methyl 4-(2-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate→3-ethyl 5-methyl 2-(bromomethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate→2-azidoethan-1-ol→3-methyl 5-propyl 6-[(2-azidoethoxy)methyl]-4-(2-chlorophenyl)-2-methyl-1,4-dihydropyridine-3,5-dicarboxylate
本站可供应的对应中间体
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