← 返回专利悬崖列表
CAS 5856-77-9
2,2-Dimethylbutanoyl chloride
登记编号：(III)122234-12-a、(IV)122234-13-a、(I)122234-14-a、(II)122234-19-a
应用背景（按来源药适应症）
血脂障碍非诺贝特/辛伐他汀高脂血症非诺贝特/辛伐他汀心脏和血管疾病非诺贝特/辛伐他汀高胆固醇血症非诺贝特/辛伐他汀
来源药（使用该中间体的合成路线）
| 品种 | 梯队 | 到期年 |
|---|---|---|
| 非诺贝特/辛伐他汀Fenofibrate/Simvastatin | Tier C · 观察 / 贸易 | - |
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
4(R)-Hydroxy-6(R)-[2-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalenyl]ethyl]tetrahydropyran-2-one→Orthoformic acid trimethyl ester→(Diethoxymethoxy)ethane→Methyl [(4R,6R)-6-[2-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl]-2-methoxy-1,3-dioxan-4-yl]acetate→Ethyl [(4R,6R)-2-ethoxy-6-[2-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl]-1,3-dioxan-4-yl]acetate→2,2-Dimethylbutanoyl chloride→(1S,3R,7S,8S,8aR)-8-[2-[(4R,6R)-2-Methoxy-6-(2-methoxy-2-oxoethyl)-1,3-dioxan-4-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate→(1S,3R,7S,8S,8aR)-8-[2-[(4R,6R)-2-Ethoxy-6-(2-ethoxy-2-oxoethyl)-1,3-dioxan-4-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate→(betaR,deltaR,1S,2S,6R,8S,8aR)-8-(2,2-Dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-beta,delta-dihydroxy-2,6-dimethyl-1-naphthaleneheptanoic acid ammonium salt
2,2-Dimethylbutanoyl chloride→S-(2-Hydroxyethyl) 2,2-dimethylbutanethioate→2-[(2,2-Dimethylbutanoyl)sulfanyl]ethyl acetate→3(R),5(R)-Dihydroxy-7-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]heptanoic acid→(betaR,deltaR,1S,2S,6R,8S,8aR)-8-(2,2-Dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-beta,delta-dihydroxy-2,6-dimethyl-1-naphthaleneheptanoic acid ammonium salt
2,2-dimethylbutanoic acid→2,2-Dimethylbutanoyl chloride→3-Mercaptopropionic acid methyl ester→Methyl 3-[(2,2-dimethylbutanoyl)sulfanyl]propanoate
本站可供应的对应中间体
目录暂未收录该靶点的在售中间体 —— 可直接发起询价，需求会进入撮合池。
本页为中间体 CAS 注册档案：同 CAS 的多条路线登记已合并；后续供应商报价与买方需求以该 CAS 为主键撮合。