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CAS 61270-71-1
(6R,7R)-7-Amino-8-oxo-3-([[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl]methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
登记编号：Cefonicid-012
应用背景（按来源药适应症）
细菌感染头孢尼西钠
来源药（使用该中间体的合成路线）
| 品种 | 梯队 | 到期年 |
|---|---|---|
| 头孢尼西钠Cefonicid Sodium | Tier C · 观察 / 贸易 | - |
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
aminomethanesulfonic acid→Phthalic anhydride→(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)methanesulfonic acid→(1,3-dioxoisoindol-2-yl)methanesulfonyl chloride→(5-sulfanyl-1H-1,2,3,4-tetrazol-1-yl)methanesulfonic acid→N-tert-butyl-1-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)methanesulfonamide→1-amino-N-tert-butylmethanesulfonamide→N-tert-butyl-1-{[(methylsulfanyl)methanethioyl]amino}methanesulfonamide→N-tert-butyl-1-(5-sulfanyl-1H-1,2,3,4-tetrazol-1-yl)methanesulfonamide→{[(methylsulfanyl)methanethioyl]amino}methanesulfonic acid→(6R,7R)-3-(Acetoxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid→(6R,7R)-7-Amino-8-oxo-3-([[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl]methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid→(1R)-2-Chloro-2-oxo-1-phenylethyl dichloroacetate→(6R,7R)-3-[(Acetyloxy)methyl]-7-[[(2R)-2-hydroxy-2-phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid→Formic acid 2-chloro-2-oxo-1(R)-phenylethyl ester<-fgf->O-Formyl-D-mandelic acid chloride<-fgf->D-O-Formylmandeolyl chloride
(6R,7R)-3-(Acetoxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid→Bis(sodium)bis[(5-sulfanyl-1H-tetrazol-1-yl)methanesulfonate]→(6R,7R)-7-Amino-8-oxo-3-([[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl]methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid→Formic acid 2-chloro-2-oxo-1(R)-phenylethyl ester<-fgf->O-Formyl-D-mandelic acid chloride<-fgf->D-O-Formylmandeolyl chloride→(6R,7R)-7-[[(2R)-2-Hydroxy-2-phenylacetyl]amino]-8-oxo-3-([[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl]methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid - N,N'-dibenzylethane-1,2-diamine
(6R,7R)-7-[[(2R)-2-(Formyloxy)-2-phenylacetyl]amino]-8-oxo-3-([[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl]methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid→(6R,7R)-7-[[(2R)-2-Hydroxy-2-phenylacetyl]amino]-8-oxo-3-([[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl]methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid→(6R,7R)-7-Amino-8-oxo-3-([[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl]methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid→Formic acid 2-chloro-2-oxo-1(R)-phenylethyl ester<-fgf->O-Formyl-D-mandelic acid chloride<-fgf->D-O-Formylmandeolyl chloride
本站可供应的对应中间体
目录暂未收录该靶点的在售中间体 —— 可直接发起询价，需求会进入撮合池。
本页为中间体 CAS 注册档案：同 CAS 的多条路线登记已合并；后续供应商报价与买方需求以该 CAS 为主键撮合。