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CAS 864244-98-4
4-(2-methyl-4-nitrophenoxy)pyridin-2-amine
登记编号：IRBIN-008
应用背景（按来源药适应症）
乳腺癌图卡替尼结直肠癌图卡替尼
来源药（使用该中间体的合成路线）
| 品种 | 梯队 | 到期年 |
|---|---|---|
| 图卡替尼Tucatinib | Tier C · 观察 / 贸易 | 2030 |
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
2-amino-5-nitrobenzonitrile→(E)-N'-(2-cyano-4-nitrophenyl)-N,N-dimethylformimidamide→(E)-N'-(4-amino-2-cyanophenyl)-N,N-dimethylformimidamide→2-amino-2-methylpropan-1-ol→(E)-N'-(2-cyano-4-(3-(1-hydroxy-2-methylpropan-2-yl)thioureido)phenyl)-N,N-dimethylformimidamide→7-(4-(l2-azaneyl)-2-methylphenoxy)-[1,2,4]triazolo[1,5-a]pyridine→1-(4-((4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)amino)quinazolin-6-yl)-3-(1-hydroxy-2-methylpropan-2-yl)thiourea→4-(2-methyl-4-nitrophenoxy)pyridin-2-amine→(E)-N,N-dimethyl-N'-(4-(2-methyl-4-nitrophenoxy)pyridin-2-yl)formimidamide→7-(2-methyl-4-nitrophenoxy)-[1,2,4]triazolo[1,5-a]pyridine→N4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine
本站可供应的对应中间体
同 CAS 多家在售供应横向对比；价格区间为供应方挂牌口径，实价以询价确认为准。
| 供应商 | 产品 | 价格区间 | 最小起订 | 货期 | 资质 |
|---|---|---|---|---|---|
| Unibest Taizhou GMP-like Site | [1,2,4]Triazolo[1,5-a]pyridin-7-ol Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Qualified Partner — East China API Works | (E)-N'-(2-cyano-4-(3-(1-hydroxy-2-methylpropan-2-yl)thioureido)phenyl)-N,N-dimethylformimidamide Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Nantong cGMP Site | (2-methyl-4-nitrophenoxy)-[1,2,4]triazolo[1,5-a]pyridine Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Taizhou GMP-like Site | 4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylaniline Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Qualified Partner — East China API Works | (E)-N'-(2-cyano-4-nitrophenyl)-N,N-dimethylformimidamide Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Nantong cGMP Site | N'-(4-Amino-2-cyanophenyl)-N,N-dimethylformamidine Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Taizhou GMP-like Site | Chloro-[1,2,4]triazolo[1,5-a]pyridine Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Qualified Partner — East China API Works | 1-(4-((4-([1,2,4]Triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)amino)quinazolin-6-yl)-3-(1-hydroxy-2-methylpropan-2-y Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Nantong cGMP Site | 1-(3-cyano-4-((dimethylamino)methyleneamin Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Taizhou GMP-like Site | (4-chloropyridin-2-yl)-N'-hydroxyformimidamide Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Qualified Partner — East China API Works | Aminopyridin-4-ol Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Nantong cGMP Site | 4-Chloropyridine-2-carboxamide Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Taizhou GMP-like Site | Methyl 4-chloropicolinate Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Qualified Partner — East China API Works | 2-Amino-4-chloropyridine Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Nantong cGMP Site | 2-Amino-4-methoxypyridine Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Taizhou GMP-like Site | 4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID AMIDE Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Qualified Partner — East China API Works | 5-Chloropyridine-2-carboxylic acid Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
本页为中间体 CAS 注册档案：同 CAS 的多条路线登记已合并；后续供应商报价与买方需求以该 CAS 为主键撮合。