维莫地吉
Tier C — Watch / tradeVismodegib
Targets：SMO
Brand：Erivedge
Indications (approved)：基底细胞癌
Regional status
Synthetic routes & intermediates3 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| VISM-001 | 218777-23-2 | pyridin-2-ylzinc(II) bromide |
| VISM-002 | 16588-26-4 | 2-bromo-1-chloro-4-nitrobenzene |
| VISM-003 | 879088-40-1 | 2-(2-chloro-5-nitrophenyl)pyridine |
| VISM-004 | 879088-41-2 | 4-chloro-3-(pyridin-2-yl)aniline |
| VISM-005 | 106904-10-3 | 2-chloro-4-(methylsulfonyl)benzoyl chloride |
| Code | CAS No. | Intermediate |
|---|---|---|
| VISM-002 | 16588-26-4 | 2-bromo-1-chloro-4-nitrobenzene |
| VISM-004 | 879088-41-2 | 4-chloro-3-(pyridin-2-yl)aniline |
| VISM-006 | 1050505-87-7 | pyridine 1-oxide |
| VISM-007 | 1619267-22-9 | 2-(2-chloro-5-nitrophenyl)pyridine 1-oxide |
| VISM-008 | 53250-83-2 | 2-chloro-4-(methylsulfonyl)benzoic acid |
| Code | CAS No. | Intermediate |
|---|---|---|
| VISM-005 | 106904-10-3 | 2-chloro-4-(methylsulfonyl)benzoyl chloride |
| VISM-009 | 74-11-3Available | 4-chlorobenzoic acid |
| VISM-010 | 42860-04-8 | 4-chloro-3-iodobenzoic acid |
| VISM-011 | 1451207-76-3 | tert-butyl (4-chloro-3-iodophenyl)carbamate |
| VISM-012 | 73183-34-3Available | 4,4,4',4',5,5,5',5'-octamethyl-2,2'-bi(1,3,2-dioxaborolane) |
| VISM-013 | 1080573-28-9 | tert-butyl (4-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate |
| VISM-014 | 109-04-6 | 2-bromopyridine |
| VISM-015 | 1403578-40-4 | tert-butyl (4-chloro-3-(pyridin-2-yl)phenyl)carbamate |
| VISM-016 | 879088-41-2 | 4-chloro-3-(pyridin-2-yl)aniline |
Frequently asked questions
What are the approved indications of Vismodegib?
Approved indications include: 基底细胞癌.
When does the Vismodegib patent expire?
No public expiry year is available for Vismodegib yet; this page updates once verified.
How many synthesis routes are recorded for Vismodegib?
3 synthesis routes are recorded; the shortest is 3 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Vismodegib intermediates?
2 intermediate CAS of Vismodegib are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Vismodegib intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24