CAS 218777-23-2

pyridin-2-ylzinc(II) bromide

Codes：VISM-001

Application context (from source-drug indications)

基底细胞癌维莫地吉多发性骨髓瘤维莫地吉淋巴瘤维莫地吉实体瘤维莫地吉血液肿瘤维莫地吉间质软骨肉瘤维莫地吉

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
维莫地吉Vismodegib	Tier C — Watch / trade	-

Position in synthesis routes (up/downstream chain)

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维莫地吉原研路线steps: 3total yield: /

pyridin-2-ylzinc(II) bromide→2-bromo-1-chloro-4-nitrobenzene→2-(2-chloro-5-nitrophenyl)pyridine→4-chloro-3-(pyridin-2-yl)aniline→2-chloro-4-(methylsulfonyl)benzoyl chloride

Intermediates available on this site

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