甲磺酸氟马替尼
Tier C — Watch / tradeFlumatinib Mesylate
Targets:Bcr-Abl
Brand:豪森昕福
Indications (approved):慢性髓细胞白血病
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

| Code | CAS No. | Intermediate |
|---|---|---|
| FLUM-001 | 637354-25-7 | 2-(methylsulfonyl)-4-(pyridin-3-yl)pyrimidine |
| FLUM-002 | 51984-61-3 | 2-methyl-5-nitropyridin-3-amine |
| FLUM-003 | 895519-80-9 | N-(2-methyl-5-nitropyridin-3-yl)-4-(pyridin-3-yl)pyrimidin-2-amine |
| FLUM-004 | 895519-81-0 | 2-methyl-N3-(4-(pyridin-3-yl)pyrimidin-2-yl)pyridine-3,5-diamine |
| FLUM-005 | 859282-11-4 | 4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)benzoic acid |
| FLUM-006 | 895519-90-1 | N-(6-methyl-5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)pyridin-3-yl)-4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)benzamide |
Frequently asked questions
What are the approved indications of Flumatinib Mesylate?
Approved indications include: 慢性髓细胞白血病.
When does the Flumatinib Mesylate patent expire?
No public expiry year is available for Flumatinib Mesylate yet; this page updates once verified.
How many synthesis routes are recorded for Flumatinib Mesylate?
1 synthesis routes are recorded; the shortest is 4 steps with 2.20 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Flumatinib Mesylate intermediates?
All intermediates in Flumatinib Mesylate routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Flumatinib Mesylate intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24