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Tier C — Watch / tradeDaprodustat · all drugs expiring in 2032 →
Targets：HIF-PHs
Brand：ダーブロック、Duvroq、Jesduvroq
Indications (approved)：贫血
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| DAPR-001 | 538-75-0 | dicyclohexylmethanediimine |
| DAPR-002 | 141-82-2Available | malonic acid |
| DAPR-003 | 35824-91-0 | 1,3-dicyclohexylpyrimidine-2,4,6(1H,3H,5H)-trione |
| DAPR-004 | 2949-22-6 | ethyl 2-isocyanatoacetate |
| DAPR-005 | 960540-96-9 | ethyl (1,3-dicyclohexyl-2,4,6-trioxohexahydropyrimidine-5-carbonyl)glycinate |
Frequently asked questions
What are the approved indications of Daprodustat?
Approved indications include: 贫血.
When does the Daprodustat patent expire?
Based on public sources, the Daprodustat patent expires in 2032.
How many synthesis routes are recorded for Daprodustat?
1 synthesis routes are recorded; the shortest is 3 steps with 116.2 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Daprodustat intermediates?
1 intermediate CAS of Daprodustat are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Daprodustat intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24