枸橼酸托烷司琼

Tier C — Watch / trade

Tropisetron Citrate

Originator

2010

First approval

Expiry (public)

No sales data

Peak sales

化学药

Type

Targets：5-HT3

Indications (approved)：化疗导致的恶心和呕吐

Regional status

China

批准上市

2010-05-07

Japan

Synthetic routes & intermediates4 routes

Originator routes × 0Optimised (non-patent) × 4Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OptimisedRoute 1Steps 1 · Total yield /

Synthetic routes & intermediates Route 1

Code	CAS No.	Intermediate
Tropisetron- 001	59496-25-2	1H-Indole-3-carbonyl chloride
Tropisetron- 002	120-29-6	3-Tropanol

OptimisedRoute 2Steps 1 · Total yield 29.1g(Tropisetron)

Synthetic routes & intermediates Route 2

Code	CAS No.	Intermediate
Tropisetron- 003	771-50-6	3-Indole formic acid
Tropisetron- 002	120-29-6	3-Tropanol

OptimisedRoute 3Steps 2 · Total yield 28.3g(Tropisetron)

Synthetic routes & intermediates Route 3

Code	CAS No.	Intermediate
Tropisetron- 003	771-50-6	3-Indolylcarboxylic acid
Tropisetron- 002	120-29-6	3-Tropanol

OptimisedRoute 4Steps 2 · Total yield 90.5g(Tropisetron- 004)

Synthetic routes & intermediates Route 4

Code	CAS No.	Intermediate
Tropisetron- 004	105826-92-4	(1R,3r,5S)-8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 1H-indole-3-carboxylate hydrogen chloride
Tropisetron- 002	120-29-6	3-Tropanol
Tropisetron- 003	771-50-6	3-Carboxyindole
Tropisetron- 001	59496-25-2	1H-Indole-3-carbonyl chloride

Frequently asked questions

What are the approved indications of Tropisetron Citrate?

Approved indications include: 化疗导致的恶心和呕吐.

When does the Tropisetron Citrate patent expire?

No public expiry year is available for Tropisetron Citrate yet; this page updates once verified.

How many synthesis routes are recorded for Tropisetron Citrate?

4 synthesis routes are recorded; the shortest is 1 steps with / total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Tropisetron Citrate intermediates?

All intermediates in Tropisetron Citrate routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Tropisetron Citrate intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-24