奈拉滨
Tier C — Watch / tradeNelarabine
Targets：POLA
Brand：Atriance、Arranon、ArranonG
Indications (approved)：前体T-淋巴母细胞性淋巴瘤白血病
Regional status
Synthetic routes & intermediates2 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| NELA-001 | 10310-21-1 | 6-chloro-9H-purin-2-amine |
| NELA-002 | 20535-83-5 | 6-methoxy-9H-purin-2-amine |
| NELA-003 | - | (R)-3-((2S,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridine-2,6(1H,3H)-dione |
| Code | CAS No. | Intermediate |
|---|---|---|
| NELA-004 | 2004-07-1 | (2R,3R,4S,5R)-2-(2-amino-6-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol |
| NELA-005 | 7803-88-5 | (2R,3R,4S,5R)-2-(2-amino-6-methoxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol |
| NELA-006 | 92123-04-1 | (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(2-amino-6-methoxy-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate |
| NELA-007 | 1001054-27-8 | ((2R,3S,4R,5R)-3-acetoxy-5-(2-amino-6-methoxy-9H-purin-9-yl)-4-hydroxytetrahydrofuran-2-yl)methyl acetate |
| NELA-008 | 1001054-28-9 | ((2R,3R,4R,5R)-3-acetoxy-5-(2-amino-6-methoxy-9H-purin-9-yl)-4-(((trifluoromethyl)sulfonyl)oxy)tetrahydrofuran-2-yl)methyl acetate |
| NELA-009 | 141140-61-6 | (2R,3R,4S,5R)-2-(acetoxymethyl)-5-(2-amino-6-methoxy-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate |
Frequently asked questions
What are the approved indications of Nelarabine?
Approved indications include: 前体T-淋巴母细胞性淋巴瘤白血病.
When does the Nelarabine patent expire?
No public expiry year is available for Nelarabine yet; this page updates once verified.
How many synthesis routes are recorded for Nelarabine?
2 synthesis routes are recorded; the shortest is 2 steps with 0.327 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Nelarabine intermediates?
All intermediates in Nelarabine routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Nelarabine intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24