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CAS 1001054-28-9
((2R,3R,4R,5R)-3-acetoxy-5-(2-amino-6-methoxy-9H-purin-9-yl)-4-(((trifluoromethyl)sulfonyl)oxy)tetrahydrofuran-2-yl)methyl acetate
Codes：NELA-008
Application context (from source-drug indications)
前体T-淋巴母细胞性淋巴瘤白血病奈拉滨Sezary综合征奈拉滨边缘带B细胞淋巴瘤奈拉滨成人T细胞白血病淋巴瘤奈拉滨华氏巨球蛋白血症奈拉滨淋巴瘤奈拉滨
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 奈拉滨Nelarabine | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(2R,3R,4S,5R)-2-(2-amino-6-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol→(2R,3R,4S,5R)-2-(2-amino-6-methoxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol→(2R,3R,4R,5R)-2-(acetoxymethyl)-5-(2-amino-6-methoxy-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate→((2R,3S,4R,5R)-3-acetoxy-5-(2-amino-6-methoxy-9H-purin-9-yl)-4-hydroxytetrahydrofuran-2-yl)methyl acetate→((2R,3R,4R,5R)-3-acetoxy-5-(2-amino-6-methoxy-9H-purin-9-yl)-4-(((trifluoromethyl)sulfonyl)oxy)tetrahydrofuran-2-yl)methyl acetate→(2R,3R,4S,5R)-2-(acetoxymethyl)-5-(2-amino-6-methoxy-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate
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