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Benzbromarone

Tier C — Watch / trade

Benzbromarone

-
Originator
1999
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type

Targets:CYP2C9

Brand:Desuric, Urinorm, Narcaricin

Indications (approved):Gout

Regional status

US
-
EU
No progress
2015-10-01
China
Approved
1999-01-01
Japan
-

Synthetic routes & intermediates3 routes

Originator routes × 1Optimised (non-patent) × 2Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 3 · Total yield 1.52 g (Benzbromaron)
BENZB-00154103-36-5BENZB-002100-73-2BENZB-0033343-80-4BENZB-0041477-19-6API · Benzbromarone
CodeCAS No.Intermediate
BENZB-00154103-36-51-(4-methoxyphenyl)pentane-1,3-dione
BENZB-002100-73-23,4-dihydro-2H-pyran-2-carbaldehyde
BENZB-0033343-80-4(2-ethylbenzofuran-3-yl)(4-methoxyphenyl)methanone
BENZB-0041477-19-6(2-ethylbenzofuran-3-yl)(4-hydroxyphenyl)methanone
OptimisedRoute 2Steps 4 · Total yield 9.8 g (Benzbromarone)
BENZB-0053337-62-0BENZB-006—BENZB-007—BENZB-0083131-63-3BENZB-009—API · Benzbromarone
CodeCAS No.Intermediate
BENZB-0053337-62-03,5-Dibromo-4-hydroxybenzoic acid
BENZB-006-3,5-Dibromo-4-[(oxan-2-yl)oxy]benzoic acid
BENZB-007-3,5-Dibromo-4-[(oxan-2-yl)oxy]benzoyl chloride
BENZB-0083131-63-32-ethylbenzofuran
BENZB-009-[3,5-Dibromo-4-[(oxan-2-yl)oxy]phenyl](2-ethyl-1-benzofuran-3-yl)methanone
OptimisedRoute 3Steps 4 · Total yield /
BENZB-0083131-63-3BENZB-010100-07-2BENZB-0113343-80-4BENZB-0121477-19-6BENZB-013100-73-2BENZB-01454103-36-5API · Benzbromarone
CodeCAS No.Intermediate
BENZB-0083131-63-32-ethylbenzofuran
BENZB-010100-07-24-methoxybenzoyl chloride
BENZB-0113343-80-4(2-ethylbenzofuran-3-yl)(4-methoxyphenyl)methanone
BENZB-0121477-19-6(2-ethylbenzofuran-3-yl)(4-hydroxyphenyl)methanone
BENZB-013100-73-23,4-dihydro-2H-pyran-2-carbaldehyde
BENZB-01454103-36-51-(4-methoxyphenyl)pentane-1,3-dione

Frequently asked questions

What are the approved indications of Benzbromarone?

Approved indications include: Gout.

When does the Benzbromarone patent expire?

No public expiry year is available for Benzbromarone yet; this page updates once verified.

How many synthesis routes are recorded for Benzbromarone?

3 synthesis routes are recorded; the shortest is 3 steps with 1.52 g (Benzbromaron) total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Benzbromarone intermediates?

All intermediates in Benzbromarone routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Benzbromarone intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-27