Golidocitinib

Tier C — Watch / trade

Golidocitinib

AstraZeneca

Originator

2024

First approval

Expiry (public)

No sales data

Peak sales

Small molecule

Type

Targets：JAK1

Indications (approved)：Peripheral T-cell lymphoma

Regional status

Phase II

2019-09-10

China

Approved

2024-06-18

Japan

Synthetic routes & intermediates2 routes

Originator routes × 0Optimised (non-patent) × 2Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OptimisedRoute 1Steps 8 · Total yield /

(I)955428-1-a6960-42-5(II)955428-1-a1446428-14-3(III)955428-1-a2091135-02-1(IV)955428-1-a2091135-03-2(V)955428-1-a3934-20-1(VI)955428-1-a2091135-04-3(VII)955428-1-a1214264-48-8(VIII)955428-1-a2091135-14-5(IX)955428-1-a2091135-13-4(X)955428-1-a2091135-23-6(XI)955428-1-a2091135-38-3(XII)955428-1-a109-01-3(XIII)955428-1-a79-33-4API · Golidocitinib

Code	CAS No.	Intermediate
(I)955428-1-a	6960-42-5	7-Nitro-1H-indole
(II)955428-1-a	1446428-14-3	1-(4-Methylbenzene-1-sulfonyl)-7-nitro-1H-indole
(III)955428-1-a	2091135-02-1	3-Bromo-1-(4-methylbenzene-1-sulfonyl)-7-nitro-1H-indole
(IV)955428-1-a	2091135-03-2	1-(4-Methylbenzene-1-sulfonyl)-7-nitro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
(V)955428-1-a	3934-20-1 Available	2-Chloropyrimidin-4-yl chloride
(VI)955428-1-a	2091135-04-3	3-(2-Chloro-4-pyrimidinyl)-N-tosyl-7-nitroindole
(VII)955428-1-a	1214264-48-8	3-(2-Chloro-4-pyrimidinyl)-7-nitroindole
(VIII)955428-1-a	2091135-14-5	3-Methoxy-1-methyl-1H-pyrazol-4-amine hydrogen chloride (1/2)
(IX)955428-1-a	2091135-13-4	N-(3-Methoxy-1-methyl-1H-pyrazol-4-yl)-4-(7-nitro-1H-indol-3-yl)pyrimidin-2-amine
(X)955428-1-a	2091135-23-6	3-[2-[(3-Methoxy-1-methyl-1H-pyrazol-4-yl)amino]pyrimidin-4-yl]-1H-indol-7-amine
(XI)955428-1-a	2091135-38-3	(2R)-2-(4-Methylpiperazin-1-yl)propanoic acid hydrogen chloride (1/2)
(XII)955428-1-a	109-01-3 Available	1-Methylpiperazine
(XIII)955428-1-a	79-33-4	(2S)-2-Hydroxypropanoic acid

OptimisedRoute 2Steps 2 · Total yield /

(I)955428-2-a—(IIa)955428-2-a3536-96-7(IIb)955428-2-a1826-67-1(III)955428-2-a—(IV)955428-2-a6960-42-5API · Golidocitinib

Code	CAS No.	Intermediate
(I)955428-2-a	-	(2-Nitrophenyl)boronic acid
(IIa)955428-2-a	3536-96-7	Chlorido(ethenyl)magnesium
(IIb)955428-2-a	1826-67-1	(Vinyl)magnesium bromide
(III)955428-2-a	-	1H-Indol-7-ylboronic acid
(IV)955428-2-a	6960-42-5	7-Nitro-1H-indole

Frequently asked questions

What are the approved indications of Golidocitinib?

Approved indications include: Peripheral T-cell lymphoma.

When does the Golidocitinib patent expire?

No public expiry year is available for Golidocitinib yet; this page updates once verified.

How many synthesis routes are recorded for Golidocitinib?

2 synthesis routes are recorded; the shortest is 2 steps with / total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Golidocitinib intermediates?

2 intermediate CAS of Golidocitinib are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.

How do I get a quote for Golidocitinib intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-27