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CAS 2091135-03-2
1-(4-Methylbenzene-1-sulfonyl)-7-nitro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
Codes: (IV)955428-1-a
Application context (from source-drug indications)
Peripheral T-cell lymphomaGolidocitinibEB病毒感染GolidocitinibViral infectionGolidocitinibHistiocytosisGolidocitinib噬血细胞性淋巴组织细胞增多症GolidocitinibInterstitial lung diseaseGolidocitinib
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Golidocitinib | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
7-Nitro-1H-indole→1-(4-Methylbenzene-1-sulfonyl)-7-nitro-1H-indole→3-Bromo-1-(4-methylbenzene-1-sulfonyl)-7-nitro-1H-indole→1-(4-Methylbenzene-1-sulfonyl)-7-nitro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole→2-Chloropyrimidin-4-yl chloride→3-(2-Chloro-4-pyrimidinyl)-N-tosyl-7-nitroindole→3-(2-Chloro-4-pyrimidinyl)-7-nitroindole→3-Methoxy-1-methyl-1H-pyrazol-4-amine hydrogen chloride (1/2)→N-(3-Methoxy-1-methyl-1H-pyrazol-4-yl)-4-(7-nitro-1H-indol-3-yl)pyrimidin-2-amine→3-[2-[(3-Methoxy-1-methyl-1H-pyrazol-4-yl)amino]pyrimidin-4-yl]-1H-indol-7-amine→(2R)-2-(4-Methylpiperazin-1-yl)propanoic acid hydrogen chloride (1/2)→1-Methylpiperazine→(2S)-2-Hydroxypropanoic acid
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