盐酸替那帕诺
Tier C — Watch / tradeTenapanor hydrochloride
Targets：NHE3
Brand：XPHOZAH、万缇乐、Ibsrela、PHOZEVEL、IBSRELA
Indications (approved)：高磷血症、慢性肾功能不全、便秘、肠易激综合征
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| TENAP-001 | 2142-63-4Available | 1-(3-bromophenyl)ethanone |
| TENAP-002 | 18523-22-3Available | 2-bromo-1-(3-bromophenyl)ethanone |
| TENAP-003 | 5013-77-4Available | 1-(2,4-dichlorophenyl)-N-methylmethanamine |
| TENAP-004 | 1234366-96-1Available | 1-(3-bromophenyl)-2-((2,4-dichlorobenzyl)(methyl)amino)ethanone |
| TENAP-005 | 1234366-97-2Available | 1-(3-bromophenyl)-2-((2,4-dichlorobenzyl)(methyl)amino)ethanol |
| TENAP-006 | 543737-10-6Available | 4-(3-bromophenyl)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinoline |
| TENAP-007 | 1870821-29-6Available | (S)-4-(3-bromophenyl)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinoline |
| TENAP-008 | - | (S)-4-(3-(benzylthio)phenyl)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinoline |
| TENAP-009 | 2232225-67-9Available | (S)-3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzene-1-sulfonyl chloride hydrochloride |
| TENAP-010 | 929-59-9Available | 2,2'-(ethane-1,2-diylbis(oxy))diethanamine |
| TENAP-011 | - | - |
| TENAP-012 | 4538-37-8Available | 1,4-diisocyanatobutane |
Frequently asked questions
What are the approved indications of Tenapanor hydrochloride?
Approved indications include: 高磷血症, 慢性肾功能不全, 便秘, 肠易激综合征.
When does the Tenapanor hydrochloride patent expire?
No public expiry year is available for Tenapanor hydrochloride yet; this page updates once verified.
How many synthesis routes are recorded for Tenapanor hydrochloride?
1 synthesis routes are recorded; the shortest is 9 steps with 246.7 mg total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Tenapanor hydrochloride intermediates?
10 intermediate CAS of Tenapanor hydrochloride are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Tenapanor hydrochloride intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24