← Back to patent-cliff list
CAS 543737-10-6
4-(3-bromophenyl)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinoline
Codes：TENAP-006
Application context (from source-drug indications)
高磷血症盐酸替那帕诺慢性肾功能不全盐酸替那帕诺便秘盐酸替那帕诺肠易激综合征盐酸替那帕诺慢性特发性便秘盐酸替那帕诺囊性纤维化盐酸替那帕诺
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 盐酸替那帕诺Tenapanor hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1-(3-bromophenyl)ethanone→2-bromo-1-(3-bromophenyl)ethanone→1-(2,4-dichlorophenyl)-N-methylmethanamine→1-(3-bromophenyl)-2-((2,4-dichlorobenzyl)(methyl)amino)ethanone→1-(3-bromophenyl)-2-((2,4-dichlorobenzyl)(methyl)amino)ethanol→4-(3-bromophenyl)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinoline→(S)-4-(3-bromophenyl)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinoline→(S)-4-(3-(benzylthio)phenyl)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinoline→(S)-3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzene-1-sulfonyl chloride hydrochloride→2,2'-(ethane-1,2-diylbis(oxy))diethanamine→TENAP-011→1,4-diisocyanatobutane
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications |
|---|---|---|---|---|---|
| Unibest Nantong cGMP Site | 4-(3-bromophenyl)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinoline Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.