依伏卡塞
Tier C — Watch / tradeEvocalcet
Targets：CaSR
Brand：Orkedia、盖优平
Indications (approved)：继发性甲状旁腺功能亢进症
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| EVOCA-001 | 109431-87-0 | (R)-tert-butyl 3-hydroxypyrrolidine-1-carboxylate |
| EVOCA-002 | 1092366-92-1 | tert-butyl (R)-3-(((2-nitrophenyl)sulfonyl)oxy)pyrrolidine-1-carboxylate |
| EVOCA-003 | 3886-70-2 | (R)-1-(naphthalen-1-yl)ethan-1-amine |
| EVOCA-004 | 1039631-63-4 | tert-butyl (S)-3-(((R)-1-(naphthalen-1-yl)ethyl)amino)pyrrolidine-1-carboxylate |
| EVOCA-005 | - | propan-2-ol compound with (S)-N-((R)-1-(naphthalen-1-yl)ethyl)pyrrolidin-3-amine (1:1) hydrochloride |
| EVOCA-006 | 870966-25-9 | (S)-N-((R)-1-(naphthalen-1-yl)ethyl)pyrrolidin-3-amine |
| EVOCA-007 | 14062-25-0 | ethyl 2-(4-bromophenyl)acetate |
| EVOCA-008 | 1666124-29-3 | ethyl 2-(4-((S)-3-(((R)-1-(naphthalen-1-yl)ethyl)amino)pyrrolidin-1-yl)phenyl)acetate hydrochloride |
| Evocalcet | 870964-67-3 | 2-(4-((S)-3-(((R)-1-(naphthalen-1-yl)ethyl)amino)pyrrolidin-1-yl)phenyl)acetic acid |
Frequently asked questions
What are the approved indications of Evocalcet?
Approved indications include: 继发性甲状旁腺功能亢进症.
When does the Evocalcet patent expire?
No public expiry year is available for Evocalcet yet; this page updates once verified.
How many synthesis routes are recorded for Evocalcet?
1 synthesis routes are recorded; the shortest is 6 steps with 12.77 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Evocalcet intermediates?
All intermediates in Evocalcet routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Evocalcet intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24