富马酸磷丙替诺福韦
Tier B — Position earlyTenofovir Alafenamide Fumarate
Targets:RT
Brand:Vemlidy、韦立得
Indications (approved):乙型肝炎、慢性乙型肝炎
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

| Code | CAS No. | Intermediate |
|---|---|---|
| TENO-001 | 73-24-5 | 9H-purin-6-amine |
| TENO-002 | 16606-55-6 | (R)-4-methyl-1,3-dioxolan-2-one |
| TENO-003 | 14047-28-0 | (R)-1-(6-amino-9H-purin-9-yl)propan-2-ol |
| TENO-004 | 31618-90-3 | (diethoxyphosphoryl)methyl 4-methylbenzenesulfonate |
| TENO-005 | 147127-20-6 | (R)-(((1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonic acid |
| TENO-006 | 379270-35-6 | phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate |
| TENO-007 | 39825-33-7 | isopropyl L-alaninate |
| TENO-008 | 379270-37-8 | isopropyl (((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-L-alaninate |
Frequently asked questions
What are the approved indications of Tenofovir Alafenamide Fumarate?
Approved indications include: 乙型肝炎, 慢性乙型肝炎.
When does the Tenofovir Alafenamide Fumarate patent expire?
No public expiry year is available for Tenofovir Alafenamide Fumarate yet; this page updates once verified.
How many synthesis routes are recorded for Tenofovir Alafenamide Fumarate?
1 synthesis routes are recorded; the shortest is 6 steps with 1.329 kg total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Tenofovir Alafenamide Fumarate intermediates?
All intermediates in Tenofovir Alafenamide Fumarate routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Tenofovir Alafenamide Fumarate intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24