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CAS 31618-90-3
(diethoxyphosphoryl)methyl 4-methylbenzenesulfonate
Codes：TENO-004
Application context (from source-drug indications)
乙型肝炎富马酸磷丙替诺福韦慢性乙型肝炎富马酸磷丙替诺福韦复发-缓解型多发性硬化富马酸磷丙替诺福韦疲劳富马酸磷丙替诺福韦HIV感染富马酸磷丙替诺福韦慢性丙型肝炎富马酸磷丙替诺福韦
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 富马酸磷丙替诺福韦Tenofovir Alafenamide Fumarate | Tier B — Position early | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
9H-purin-6-amine→(R)-4-methyl-1,3-dioxolan-2-one→(R)-1-(6-amino-9H-purin-9-yl)propan-2-ol→(diethoxyphosphoryl)methyl 4-methylbenzenesulfonate→(R)-(((1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonic acid→phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate→isopropyl L-alaninate→isopropyl (((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-L-alaninate
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