硫酸艾沙康唑
Tier C — Watch / tradeIsavuconazonium Sulfate · all drugs expiring in 2029 →
Targets：CYP51
Brand：康新博、Cresemba
Indications (approved)：毛霉菌目感染、曲霉菌属感染、隐孢子虫感染、真菌感染
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| ISAV-001 | 17392-83-5Available | methyl (R)-2-hydroxypropanoate |
| ISAV-002 | 135206-87-0Available | (R)-2-hydroxy-1-morpholinopropan-1-one |
| ISAV-003 | 135270-08-5Available | (2R)-1-morpholino-2-((tetrahydro-2H-pyran-2-yl)oxy)propan-1-one |
| ISAV-004 | 399-94-0Available | 2-bromo-1,4-difluorobenzene |
| ISAV-005 | 241479-69-6Available | (2R)-1-(2,5-difluorophenyl)-2-((tetrahydro-2H-pyran-2-yl)oxy)propan-1-one |
| ISAV-006 | 241479-70-9Available | 2-((1R)-1-(2-(2,5-difluorophenyl)oxiran-2-yl)ethoxy)tetrahydro-2H-pyran |
| ISAV-007 | 288-88-0Available | 1H-1,2,4-triazole |
| ISAV-008 | 241479-71-0Available | (3R)-2-(2,5-difluorophenyl)-3-((tetrahydro-2H-pyran-2-yl)oxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol |
| ISAV-009 | 241479-72-1Available | (2R,3R)-2-(2,5-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol |
| ISAV-010 | 241479-73-2Available | 1-(((2R,3S)-2-(2,5-difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole |
| ISAV-011 | 241479-74-3Available | (2S,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanenitrile |
| ISAV-012 | 368421-58-3Available | (2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide |
| ISAV-013 | 20099-89-2Available | 4-(2-bromoacetyl)benzonitrile |
| ISAV-014 | 241479-67-4Available | 4-(2-((2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl)thiazol-4-yl)benzonitrile |
| ISAV-015 | 338990-31-1Available | (2-(((1-chloroethoxy)carbonyl)(methyl)amino)pyridin-3-yl)methyl 2-((tert-butoxycarbonyl)(methyl)amino)acetate |
| ISAV-016 | 338990-63-9Available | 4-(1-(((3-((2-((tert-butoxycarbonyl)(methyl)amino)acetoxy)methyl)pyridin-2-yl)(methyl)carbamoyl)oxy)ethyl)-1-((2R,3R)-3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,5-difluorophenyl)-2-hydroxybutyl)-1H-1,2,4-triazol-4-ium chloride |
| ISAV-017 | 2942-59-8Available | 2-chloronicotinic acid |
| ISAV-018 | 49609-84-9Available | 2-chloronicotinoyl chloride |
| ISAV-019 | 232951-83-6Available | tert-butyl 2-chloronicotinate |
| ISAV-020 | 338990-70-8Available | tert-butyl 2-(methylamino)nicotinate |
| ISAV-021 | 32399-12-5Available | (2-(methylamino)pyridin-3-yl)methanol |
| ISAV-022 | 50893-53-3Available | 1-chloroethyl carbonochloridate |
Frequently asked questions
What are the approved indications of Isavuconazonium Sulfate?
Approved indications include: 毛霉菌目感染, 曲霉菌属感染, 隐孢子虫感染, 真菌感染.
When does the Isavuconazonium Sulfate patent expire?
Based on public sources, the Isavuconazonium Sulfate patent expires in 2029.
How many synthesis routes are recorded for Isavuconazonium Sulfate?
1 synthesis routes are recorded; the shortest is 17 steps with 32.8 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Isavuconazonium Sulfate intermediates?
22 intermediate CAS of Isavuconazonium Sulfate are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Isavuconazonium Sulfate intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24