盐酸卡马替尼
Tier C — Watch / tradeCapmatinib Hydrochloride · all drugs expiring in 2032 →
Targets：c-Met
Brand：Tabrecta、妥瑞达
Indications (approved)：非小细胞肺癌
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| CAPMA-001 | 153556-42-4Available | 4-bromo-3-fluorobenzoic acid |
| CAPMA-002 | 695188-21-7Available | 4-bromo-3-fluorobenzoyl chloride |
| CAPMA-003 | 343564-56-7Available | 4-bromo-3-fluoro-N-methoxy-N-methylbenzamide |
| CAPMA-004 | 304445-49-6Available | 1-(4-bromo-3-fluorophenyl)ethanone |
| CAPMA-005 | 1006875-89-3Available | 1-(4-bromo-3-fluorophenyl)-2,2-dihydroxyethanone |
| CAPMA-006 | 1029714-83-7Available | 2-(4-bromo-3-fluorophenyl)-2-oxoacetaldehyde |
| CAPMA-007 | 1006875-90-6Available | 1-(4-bromo-3-fluorophenyl)-2,2-diethoxyethanone |
| CAPMA-008 | 2200-97-7Available | - |
| CAPMA-009 | 1029714-84-8Available | 6-(4-bromo-3-fluorophenyl)-1,2,4-triazin-3-amine |
| CAPMA-010 | 1029714-85-9Available | 2-chloro-3-(quinolin-6-yl)propanal |
| CAPMA-011 | 1029714-86-0Available | 6-((2-(4-bromo-3-fluorophenyl)imidazo[1,2-b][1,2,4]triazin-7-yl)methyl)quinoline |
| CAPMA-012 | 1029714-87-1Available | 2-fluoro-4-(7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl)benzonitrile |
| CAPMA-013 | 1029714-88-2Available | 2-fluoro-4-(7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl)benzoic acid |
| CAPMA-014 | 5332-25-2Available | 6-bromoquinoline |
| CAPMA-015 | 476660-18-1Available | 3-(quinolin-6-yl)propanal |
| Capmatinib | 1029712-80-8Available | 2-fluoro-N-methyl-4-(7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl)benzamide |
Frequently asked questions
What are the approved indications of Capmatinib Hydrochloride?
Approved indications include: 非小细胞肺癌.
When does the Capmatinib Hydrochloride patent expire?
Based on public sources, the Capmatinib Hydrochloride patent expires in 2032.
How many synthesis routes are recorded for Capmatinib Hydrochloride?
1 synthesis routes are recorded; the shortest is 12 steps with 260 mg total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Capmatinib Hydrochloride intermediates?
16 intermediate CAS of Capmatinib Hydrochloride are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Capmatinib Hydrochloride intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24