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CAS 1029714-87-1
2-fluoro-4-(7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl)benzonitrile
Codes：CAPMA-012
Application context (from source-drug indications)
非小细胞肺癌盐酸卡马替尼
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 盐酸卡马替尼Capmatinib Hydrochloride | Tier C — Watch / trade | 2032 |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
4-bromo-3-fluorobenzoic acid→4-bromo-3-fluorobenzoyl chloride→4-bromo-3-fluoro-N-methoxy-N-methylbenzamide→1-(4-bromo-3-fluorophenyl)ethanone→1-(4-bromo-3-fluorophenyl)-2,2-dihydroxyethanone→2-(4-bromo-3-fluorophenyl)-2-oxoacetaldehyde→1-(4-bromo-3-fluorophenyl)-2,2-diethoxyethanone→CAPMA-008→6-(4-bromo-3-fluorophenyl)-1,2,4-triazin-3-amine→2-chloro-3-(quinolin-6-yl)propanal→6-((2-(4-bromo-3-fluorophenyl)imidazo[1,2-b][1,2,4]triazin-7-yl)methyl)quinoline→2-fluoro-4-(7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl)benzonitrile→2-fluoro-4-(7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl)benzoic acid→6-bromoquinoline→3-(quinolin-6-yl)propanal→2-fluoro-N-methyl-4-(7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl)benzamide
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications |
|---|---|---|---|---|---|
| Qualified Partner — East China API Works | 1-[2-Chloro-1-hydroxy-3-(6-quinolinyl)propyl]-2,5-pyrrolidinedione Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.