Fedratinib
Tier C — Watch / tradeFedratinib
Targets：JAK2、FLT3
Brand：Inrebic
Indications (approved)：骨髓纤维化、脾大
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| FEDR-001 | 308283-47-8 | 3-bromo-N-(tert-butyl)benzenesulfonamide |
| FEDR-002 | 14394-70-8 | 2-chloro-5-methylpyrimidin-4-amine |
| FEDR-003 | 936092-53-4 | N-(tert-butyl)-3-((2-chloro-5-methylpyrimidin-4-yl)amino)benzenesulfonamide |
| FEDR-004 | 50609-01-3 | 4-(2-(pyrrolidin-1-yl)ethoxy)aniline |
Frequently asked questions
What are the approved indications of Fedratinib?
Approved indications include: 骨髓纤维化, 脾大.
When does the Fedratinib patent expire?
No public expiry year is available for Fedratinib yet; this page updates once verified.
How many synthesis routes are recorded for Fedratinib?
1 synthesis routes are recorded; the shortest is 2 steps with 40 mg total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Fedratinib intermediates?
All intermediates in Fedratinib routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Fedratinib intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24