醋酸伏诺拉生
Tier C — Watch / tradeVonoprazan Acetate · all drugs expiring in 2029 →
Targets：H+/K+ ATPase
Indications (approved)：消化性溃疡出血
Regional status
Synthetic routes & intermediates4 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| VONO-001 | 445-27-2Available | 1-(2-fluorophenyl)ethanone |
| VONO-002 | 655-15-2Available | 2-bromo-1-(2-fluorophenyl)ethanone |
| VONO-003 | 105-56-6Available | ethyl 2-cyanoacetate |
| VONO-004 | 881673-98-9Available | ethyl 2-cyano-4-(2-fluorophenyl)-4-oxobutanoate |
| VONO-005 | 881674-01-7Available | ethyl 2-chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carboxylate |
| VONO-006 | 881674-06-2Available | ethyl 5-(2-fluorophenyl)-1H-pyrrole-3-carboxylate |
| VONO-007 | 881674-58-4Available | (5-(2-fluorophenyl)-1H-pyrrol-3-yl)methanol |
| VONO-008 | 881674-56-2Available | 5-(2-fluorophenyl)-1H-pyrrole-3-carbaldehyde |
| VONO-009 | 42899-76-3Available | pyridine-3-sulfonyl chloride hydrochloride |
| VONO-010 | 881677-11-8Available | 5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde |
| VONO-011 | 110-17-8Available | fumaric acid |
| VONO-012 | 636-73-7Available | pyridine-3-sulfonic acid |
| Code | CAS No. | Intermediate |
|---|---|---|
| VONO-008 | 881674-56-2Available | 5-(2-fluorophenyl)-1H-pyrrole-3-carbaldehyde |
| VONO-013 | 1610043-62-3Available | 1-(5-(2-fluorophenyl)-1H-pyrrol-3-yl)-N-methylmethanamine |
| VONO-014 | 1610043-63-4Available | tert-butyl ((5-(2-fluorophenyl)-1H-pyrrol-3-yl)methyl)(methyl)carbamate |
| VONO-015 | 16133-25-8Available | pyridine-3-sulfonyl chloride |
| VONO-016 | 1831110-76-9Available | tert-butyl ((5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methyl)(methyl)carbamate |
| VONO-011 | 110-17-8Available | fumaric acid |
| Code | CAS No. | Intermediate |
|---|---|---|
| VONO-001 | 445-27-2Available | 1-(2-fluorophenyl)ethanone |
| VONO-002 | 655-15-2Available | 2-bromo-1-(2-fluorophenyl)ethanone |
| VONO-017 | - | 2-(2-fluorobenzoyl)malononitrile |
| VONO-018 | - | 2-chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile |
| VONO-019 | 881674-56-2Available | 5-(2-fluorophenyl)-1H-pyrrole-3-carbaldehyde |
| VONO-015 | 16133-25-8Available | pyridine-3-sulfonyl chloride |
| VONO-010 | 881677-11-8Available | 5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde |
| Vonoprazan Fumarate | 1260141-27-2Available | - |
| Code | CAS No. | Intermediate |
|---|---|---|
| VONO-020 | 1240948-77-9Available | 5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile |
| VONO-015 | 16133-25-8Available | pyridine-3-sulfonyl chloride |
| VONO-021 | 1807642-39-2Available | 5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbonitrile |
| VONO-022 | 1807642-41-6Available | (5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methanamine |
Frequently asked questions
What are the approved indications of Vonoprazan Acetate?
Approved indications include: 消化性溃疡出血.
When does the Vonoprazan Acetate patent expire?
Based on public sources, the Vonoprazan Acetate patent expires in 2029.
How many synthesis routes are recorded for Vonoprazan Acetate?
4 synthesis routes are recorded; the shortest is 3 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Vonoprazan Acetate intermediates?
20 intermediate CAS of Vonoprazan Acetate are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Vonoprazan Acetate intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24