琥珀酸瑞波西利
Tier A — Act nowRibociclib Succinate · all drugs expiring in 2029 →
Targets：CDK6、CDK4
Brand：凯丽隆、Kisqali
Indications (approved)：乳腺癌
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| RIBO-001 | 36082-50-5Available | 5-bromo-2,4-dichloropyrimidine |
| RIBO-002 | 1003-03-8Available | cyclopentanamine |
| RIBO-003 | 733039-20-8Available | 5-bromo-2-chloro-N-cyclopentylpyrimidin-4-amine |
| RIBO-004 | 107-19-7Available | prop-2-yn-1-ol |
| RIBO-005 | 1374639-76-5Available | 3-(2-chloro-4-(cyclopentylamino)pyrimidin-5-yl)prop-2-yn-1-ol |
| RIBO-006 | 1374639-77-6Available | (2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)methanol |
| RIBO-007 | 124-40-3Available | dimethylamine |
| RIBO-008 | 1211443-61-6Available | 2-chloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide |
| RIBO-009 | 571188-59-5Available | tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate |
| RIBO-010 | 1374639-78-7Available | tert-butyl 4-(6-((7-cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate |
| RIBO-011 | 52092-47-4Available | 5-chloro-2-nitropyridine |
| RIBO-012 | 110-85-0Available | piperazine |
| RIBO-013 | 775288-71-6Available | 1-(6-nitropyridin-3-yl)piperazine |
| RIBO-014 | 571189-16-7Available | tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate |
Frequently asked questions
What are the approved indications of Ribociclib Succinate?
Approved indications include: 乳腺癌.
When does the Ribociclib Succinate patent expire?
Based on public sources, the Ribociclib Succinate patent expires in 2029.
How many synthesis routes are recorded for Ribociclib Succinate?
1 synthesis routes are recorded; the shortest is 9 steps with 45.7 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Ribociclib Succinate intermediates?
14 intermediate CAS of Ribociclib Succinate are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Ribociclib Succinate intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24