甲磺酸阿帕替尼
Tier C — Watch / tradeApatinib Mesylate
Targets：VEGFR2
Brand：艾坦、Aitan
Indications (approved)：乳腺癌、胃癌
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| APAT-001 | 77-57-6 | 1-phenylcyclopentanecarbonitrile |
| APAT-002 | 91392-33-5 | 1-(4-nitrophenyl)cyclopentanecarbonitrile |
| APAT-003 | 115279-73-7 | 1-(4-aminophenyl)cyclopentanecarbonitrile |
| APAT-004 | 49609-84-9Available | 2-chloronicotinoyl chloride |
| APAT-005 | 1158560-99-6 | 2-chloro-N-(4-(1-cyanocyclopentyl)phenyl)nicotinamide |
| APAT-006 | 3731-53-1 | pyridin-4-ylmethanamine |
Frequently asked questions
What are the approved indications of Apatinib Mesylate?
Approved indications include: 乳腺癌, 胃癌.
When does the Apatinib Mesylate patent expire?
No public expiry year is available for Apatinib Mesylate yet; this page updates once verified.
How many synthesis routes are recorded for Apatinib Mesylate?
1 synthesis routes are recorded; the shortest is 5 steps with 161.5 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Apatinib Mesylate intermediates?
1 intermediate CAS of Apatinib Mesylate are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Apatinib Mesylate intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24