Enarodustat
Tier C — Watch / tradeEnarodustat
Targets：HIF-PHs
Brand：エナロイ, Enaroy
Indications (approved)：Chronic renal impairment, Anaemia
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| ENARO-001 | 262423-77-8 | 2,4-dichloronicotinic acid |
| ENARO-002 | 1151655-02-5 | tert-butyl 5-methylpyrazine-2-carboxylate |
| ENARO-003 | 1262132-92-2 | tert-butyl 2,4-dichloronicotinate |
| ENARO-004 | 1262132-93-3 | tert-butyl 4-(benzyloxy)-2-chloronicotinate |
| ENARO-005 | 1262132-94-4 | tert-butyl 4-(benzyloxy)-2-hydrazinylnicotinate |
| ENARO-006 | 1262132-95-5 | tert-butyl 7-(benzyloxy)-[1,2,4]triazolo[4,3-a]pyridine-8-carboxylate |
| ENARO-007 | 1262132-96-6 | tert-butyl 7-(benzyloxy)-[1,2,4]triazolo[1,5-a]pyridine-8-carboxylate |
| ENARO-008 | 1262132-97-7 | tert-butyl 7-(benzyloxy)-5-iodo-[1,2,4]triazolo[1,5-a]pyridine-8-carboxylate |
| ENARO-009 | 536-74-3 | ethynylbenzene |
| ENARO-010 | 1262133-02-7 | tert-butyl 7-(benzyloxy)-5-(phenylethynyl)-[1,2,4]triazolo[1,5-a]pyridine-8-carboxylate |
| ENARO-011 | 1262133-04-9 | 7-(benzyloxy)-5-(phenylethynyl)-[1,2,4]triazolo[1,5-a]pyridine-8-carboxylic acid compound with methanesulfonic acid (1:1) |
| ENARO-012 | 623-33-6 | ethyl glycinate hydrochloride |
| ENARO-013 | 1262133-05-0 | ethyl (7-(benzyloxy)-5-(phenylethynyl)-[1,2,4]triazolo[1,5-a]pyridine-8-carbonyl)glycinate |
| ENARO-014 | 1262133-06-1 | ethyl (7-hydroxy-5-phenethyl-[1,2,4]triazolo[1,5-a]pyridine-8-carbonyl)glycinate |
| Enarodustat | 1262132-81-9 | - |
Frequently asked questions
What are the approved indications of Enarodustat?
Approved indications include: Chronic renal impairment, Anaemia.
When does the Enarodustat patent expire?
No public expiry year is available for Enarodustat yet; this page updates once verified.
How many synthesis routes are recorded for Enarodustat?
1 synthesis routes are recorded; the shortest is 11 steps with 2.16 g (Enarodustat) total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Enarodustat intermediates?
All intermediates in Enarodustat routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Enarodustat intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-27