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CAS 1262133-04-9
7-(benzyloxy)-5-(phenylethynyl)-[1,2,4]triazolo[1,5-a]pyridine-8-carboxylic acid compound with methanesulfonic acid (1:1)
Codes: ENARO-011
Application context (from source-drug indications)
Chronic renal impairmentEnarodustatAnaemiaEnarodustat
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Enarodustat | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2,4-dichloronicotinic acid→tert-butyl 5-methylpyrazine-2-carboxylate→tert-butyl 2,4-dichloronicotinate→tert-butyl 4-(benzyloxy)-2-chloronicotinate→tert-butyl 4-(benzyloxy)-2-hydrazinylnicotinate→tert-butyl 7-(benzyloxy)-[1,2,4]triazolo[4,3-a]pyridine-8-carboxylate→tert-butyl 7-(benzyloxy)-[1,2,4]triazolo[1,5-a]pyridine-8-carboxylate→tert-butyl 7-(benzyloxy)-5-iodo-[1,2,4]triazolo[1,5-a]pyridine-8-carboxylate→ethynylbenzene→tert-butyl 7-(benzyloxy)-5-(phenylethynyl)-[1,2,4]triazolo[1,5-a]pyridine-8-carboxylate→7-(benzyloxy)-5-(phenylethynyl)-[1,2,4]triazolo[1,5-a]pyridine-8-carboxylic acid compound with methanesulfonic acid (1:1)→ethyl glycinate hydrochloride→ethyl (7-(benzyloxy)-5-(phenylethynyl)-[1,2,4]triazolo[1,5-a]pyridine-8-carbonyl)glycinate→ethyl (7-hydroxy-5-phenethyl-[1,2,4]triazolo[1,5-a]pyridine-8-carbonyl)glycinate→Enarodustat
Intermediates available on this site
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