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Tecovirimat

Tier C — Watch / trade

Tecovirimat

Siga Technologies Inc
Originator
2018
First approval
-
Expiry (public)
No sales data
Peak sales
化学药
Type

Targetsenv

BrandTpoxx、Arestvyr

Indications (approved)猴痘病毒感染、牛痘、天花感染、痘病毒感染、牛痘病

Regional status

US
批准上市
2018-07-13
EU
批准上市
2022-01-06
China
-
Japan
批准上市
2024-12-27

Synthetic routes & intermediates4 routes

Originator routes × 1Optimised (non-patent) × 3Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 2 · Total yield 152.00 mg (Tecovirimat)
Synthetic routes & intermediates Route 1
CodeCAS No.Intermediate
TECO-001544-25-2cyclohepta-1,3,5-triene
TECO-002108-31-6furan-2,5-dione
TECO-003944-41-2(3aR,4R,4aR,5aS,6S,6aS)-4,4a,5,5a,6,6a-hexahydro-1H-4,6-ethenocyclopropa[f]isobenzofuran-1,3(3aH)-dione
TECO-004339-59-34-(trifluoromethyl)benzohydrazide
OptimisedRoute 2Steps 2 · Total yield 0.84 g (Tecovirimat)
Synthetic routes & intermediates Route 2
CodeCAS No.Intermediate
TECO-001544-25-2cyclohepta-1,3,5-triene
TECO-002108-31-6furan-2,5-dione
TECO-004339-59-34-(trifluoromethyl)benzohydrazide
TECO-0051565736-80-2N-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-4-(trifluoromethyl)benzamide
OptimisedRoute 3Steps 4 · Total yield 0.75 g (Tecovirimat)
Synthetic routes & intermediates Route 3
CodeCAS No.Intermediate
TECO-001544-25-2cyclohepta-1,3,5-triene
TECO-002108-31-6furan-2,5-dione
TECO-0051565736-80-2N-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-4-(trifluoromethyl)benzamide
TECO-0061565736-82-4tert-butyl (2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)carbamate
TECO-0071565736-85-71-amino-1H-pyrrole-2,5-dione hydrochloride
TECO-008329-15-74-(trifluoromethyl)benzoyl chloride
OptimisedRoute 4Steps 5 · Total yield 55.00 mg (Tecovirimat)
Synthetic routes & intermediates Route 4
CodeCAS No.Intermediate
TECO-001544-25-2cyclohepta-1,3,5-triene
TECO-002108-31-6furan-2,5-dione
TECO-003944-41-2(3aR,4R,4aR,5aS,6S,6aS)-4,4a,5,5a,6,6a-hexahydro-1H-4,6-ethenocyclopropa[f]isobenzofuran-1,3(3aH)-dione
TECO-0091565736-74-4tert-butyl ((3aR,4R,4aR,5aS,6S,6aS)-1,3-dioxo-3,3a,4,4a,5,5a,6,6a-octahydro-4,6-ethenocyclopropa[f]isoindol-2(1H)-yl)carbamate
TECO-0101565736-79-9(3aR,4R,4aR,5aS,6S,6aS)-2-amino-4,4a,5,5a,6,6a-hexahydro-4,6-ethenocyclopropa[f]isoindole-1,3(2H,3aH)-dione hydrochloride
TECO-0111711-02-04-iodobenzoyl chloride
TECO-0121565736-87-9N-((3aR,4R,4aR,5aS,6S,6aS)-1,3-dioxo-3,3a,4,4a,5,5a,6,6a-octahydro-4,6-ethenocyclopropa[f]isoindol-2(1H)-yl)-4-iodobenzamide
TECO-013680-15-9methyl 2,2-difluoro-2-(fluorosulfonyl)acetate

Frequently asked questions

What are the approved indications of Tecovirimat?

Approved indications include: 猴痘病毒感染, 牛痘, 天花感染, 痘病毒感染, 牛痘病.

When does the Tecovirimat patent expire?

No public expiry year is available for Tecovirimat yet; this page updates once verified.

How many synthesis routes are recorded for Tecovirimat?

4 synthesis routes are recorded; the shortest is 2 steps with 152.00 mg (Tecovirimat) total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Tecovirimat intermediates?

All intermediates in Tecovirimat routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Tecovirimat intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-24