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Tier C — Watch / tradeBetrixaban · all drugs expiring in 2028 →
Targets：F10
Brand：Bevyxxa
Indications (approved)：静脉血栓栓塞、肝功能衰退、心房颤动、心房扑动、肾功能不全、血栓栓塞
Regional status
Synthetic routes & intermediates2 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| BETR-001 | 1882-69-5 | 5-methoxy-2-nitrobenzoic acid |
| BETR-002 | 1072-98-6 | 5-chloropyridin-2-amine |
| BETR-003 | 280773-16-2 | N-(5-chloropyridin-2-yl)-5-methoxy-2-nitrobenzamide |
| BETR-004 | 585544-20-3 | 6-chloro-N-neopentylnicotinamide |
| BETR-005 | 6068-72-0 | 4-cyanobenzoyl chloride |
| BETR-006 | 330942-01-3 | N-(5-chloropyridin-2-yl)-2-(4-cyanobenzamido)-5-methoxybenzamide |
| Code | CAS No. | Intermediate |
|---|---|---|
| BETR-004 | 585544-20-3 | 6-chloro-N-neopentylnicotinamide |
| BETR-007 | 619-65-8 | 4-cyanobenzoic acid |
| BETR-008 | 1129-35-7 | methyl 4-cyanobenzoate |
| BETR-009 | 764659-41-8 | methyl 4-(N,N-dimethylcarbamimidoyl)benzoate |
| BETR-010 | 210963-78-3 | 4-(N,N-dimethylcarbamimidoyl)benzoic acid hydrochloride |
Frequently asked questions
What are the approved indications of Betrixaban?
Approved indications include: 静脉血栓栓塞, 肝功能衰退, 心房颤动, 心房扑动, 肾功能不全, 血栓栓塞.
When does the Betrixaban patent expire?
Based on public sources, the Betrixaban patent expires in 2028.
How many synthesis routes are recorded for Betrixaban?
2 synthesis routes are recorded; the shortest is 4 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Betrixaban intermediates?
All intermediates in Betrixaban routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Betrixaban intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24