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大麻二酚

Tier B — Position early

Cannabidiol

Gw Pharmaceuticals Plc
Originator
2018
First approval
-
Expiry (public)
$1.06B ▲
Peak sales
化学药
Type

Targets:CB1、CB2、Serotonin 5-HT1 receptors、Transient receptor potential channels

Brand:Cannepil、Epidyolex、Epidiolex

Indications (approved):结节性脑硬化、Dravet综合征、Lennox Gastaut综合征

Regional status

US
批准上市
2018-06-25
EU
批准上市
2019-09-19
China
-
Japan
-

Synthetic routes & intermediates2 routes

Originator routes × 1Optimised (non-patent) × 1Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 3 · Total yield 17.00-19.00 g
Synthetic routes & intermediates Route 1
CodeCAS No.Intermediate
CANN-0011244-58-2(1'R,2'R)-2,6-dihydroxy-5'-methyl-4-pentyl-2'-(prop-1-en-2-yl)-1',2',3',4'-tetrahydro-[1,1'-biphenyl]-3-carboxylic acid
CANN-00213956-29-1(1'R,2'R)-5'-methyl-4-pentyl-2'-(prop-1-en-2-yl)-1',2',3',4'-tetrahydro-[1,1'-biphenyl]-2,6-diol
CANN-00399-33-23,5-dinitrobenzoyl chloride
CANN-004-(1'R,2'R)-5'-methyl-4-pentyl-2'-(prop-1-en-2-yl)-1',2',3',4'-tetrahydro-[1,1'-biphenyl]-2,6-diyl bis(3,5-dinitrobenzoate)
OptimisedRoute 2Steps 3 · Total yield 11.00 mg
Synthetic routes & intermediates Route 2
CodeCAS No.Intermediate
CANN-00522976-40-51,3-dimethoxy-5-pentylbenzene
CANN-006-(1R,4S,7R)-3-bromo-7-(bromomethyl)-1,7-dimethylbicyclo[2.2.1]heptan-2-one
CANN-007-(1R,4R,7R)-7-(bromomethyl)-3-(2,6-dimethoxy-4-pentylphenyl)-1,7-dimethylbicyclo[2.2.1]heptan-2-one
CANN-008814-49-3diethyl phosphorochloridate
CANN-009140633-48-3(1R,6R)-2',6'-dimethoxy-3-methyl-4'-pentyl-6-(prop-1-en-2-yl)-1,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl diethyl phosphate

Frequently asked questions

What are the approved indications of Cannabidiol?

Approved indications include: 结节性脑硬化, Dravet综合征, Lennox Gastaut综合征.

When does the Cannabidiol patent expire?

No public expiry year is available for Cannabidiol yet; this page updates once verified.

How many synthesis routes are recorded for Cannabidiol?

2 synthesis routes are recorded; the shortest is 3 steps with 17.00-19.00 g total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Cannabidiol intermediates?

All intermediates in Cannabidiol routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Cannabidiol intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-24