地西他滨
Tier C — Watch / tradeDecitabine
Targets：DNMT1
Brand：Dacogen、达珂
Indications (approved)：过敏反应、睫状肌麻痹、低血压、急性髓细胞样白血病、骨髓增生异常综合征
Regional status
Synthetic routes & intermediates3 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| DECI-001 | - | ((2R,3S)-3-acetoxy-5-isocyanatotetrahydrofuran-2-yl)methyl acetate |
| DECI-002 | 2986-19-8 | methyl carbamimidothioate |
| DECI-003 | - | ((2R,3S)-3-acetoxy-5-(3-((E)-amino(methylthio)methylene)ureido)tetrahydrofuran-2-yl)methyl acetate |
| DECI-004 | 463-78-5 | methanetriol |
| DECI-005 | - | ((2R,3S,5R)-3-acetoxy-5-(4-(methylthio)-2-oxo-1,3,5-triazin-1(2H)-yl)tetrahydrofuran-2-yl)methyl acetate |
| Code | CAS No. | Intermediate |
|---|---|---|
| DECI-006 | 533-67-5 | (3S,4R)-3,4,5-trihydroxypentanal |
| DECI-007 | 60134-26-1 | (2R,3R,5R)-2-(hydroxymethyl)-5-methoxytetrahydrofuran-3-ol |
| DECI-008 | 1173110-83-2 | ((2R,3S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)oxy)-5-methoxytetrahydrofuran-2-yl)methyl ((9H-fluoren-9-yl)methyl) carbonate |
| DECI-009 | 1416776-62-9 | ((2R,3S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)oxy)-5-chlorotetrahydrofuran-2-yl)methyl ((9H-fluoren-9-yl)methyl) carbonate |
| DECI-010 | 52523-35-0 | N-(trimethylsilyl)-4-((trimethylsilyl)oxy)-1,3,5-triazin-2-amine |
| DECI-011 | 27607-77-8 | trimethylsilyl trifluoromethanesulfonate |
| DECI-012 | 102851-36-5 | ((2R,3S,5R)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)oxy)-5-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)tetrahydrofuran-2-yl)methyl ((9H-fluoren-9-yl)methyl) carbonate |
| DECI-013 | 931-86-2 | 4-amino-1,3,5-triazin-2(1H)-one |
| Code | CAS No. | Intermediate |
|---|---|---|
| DECI-010 | 52523-35-0 | N-(trimethylsilyl)-4-((trimethylsilyl)oxy)-1,3,5-triazin-2-amine |
| DECI-013 | 931-86-2 | 4-amino-1,3,5-triazin-2(1H)-one |
| DECI-014 | 10416-59-8 | trimethylsilyl (E)-N-(trimethylsilyl)acetimidate |
| DECI-015 | 4594-52-9 | (4S,5R)-5-(acetoxymethyl)tetrahydrofuran-2,4-diyl diacetate |
Frequently asked questions
What are the approved indications of Decitabine?
Approved indications include: 过敏反应, 睫状肌麻痹, 低血压, 急性髓细胞样白血病, 骨髓增生异常综合征.
When does the Decitabine patent expire?
No public expiry year is available for Decitabine yet; this page updates once verified.
How many synthesis routes are recorded for Decitabine?
3 synthesis routes are recorded; the shortest is 2 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Decitabine intermediates?
All intermediates in Decitabine routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Decitabine intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24