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TLX-591 companion diagnostic (Telix Pharmaceuticals)

Tier C — Watch / trade

TLX-591 companion diagnostic (Telix Pharmaceuticals)

Anmi
Originator
2020
First approval
-
Expiry (public)
No sales data
Peak sales
In vivo diagnostic
Type

Targets:PSMA

Brand:ILLUCCIX, Gallium Ga 68 Psma-11, Locametz, Illuccix

Indications (approved):Prostate cancer, Diagnostic agent

Regional status

US
Approved
2020-12-01
EU
Approved
2022-12-09
China
Approved
2025-11-25
Japan
-

Synthetic routes & intermediates2 routes

Originator routes × 0Optimised (non-patent) × 2Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OptimisedRoute 1Steps 4 · Total yield /
(I)828549-1-a—(II)828549-1-a88574-06-5(III)828549-1-a—(IV)828549-1-a1366302-51-3(V)828549-1-a,(V)828549-1-b1309876-75-2(VI)828549-1-a1366302-52-4API · TLX-591 companion diagnostic (Telix Pharmaceuticals)
CodeCAS No.Intermediate
(I)828549-1-a-Resin bound (2S)-6-amino-2-([[(2S)-1,5-di-tert-butoxy-1,5-dioxopentan-2-yl]carbamoyl]amino)hexanoic acid
(II)828549-1-a88574-06-56-([[(9H-Fluoren-9-yl)methoxy]carbonyl]amino)hexanoic acid
(III)828549-1-a-Resin bound (2S)-6-[(6-Aminohexanoyl)amino]-2-([[(2S)-1,5-di-tert-butoxy-1,5-dioxopentan-2-yl]carbamoyl]amino)hexanoic acid
(IV)828549-1-a1366302-51-3(2S)-6-[(6-Aminohexanoyl)amino]-2-([[(2S)-1,5-di-tert-butoxy-1,5-dioxopentan-2-yl]carbamoyl]amino)hexanoic acid
(V)828549-1-a,(V)828549-1-b1309876-75-23-(3-[[(Carboxymethyl)[2-[(carboxymethyl)([2-hydroxy-5-[3-oxo-3-(2,3,5,6-tetrafluorophenoxy)propyl]phenyl]methyl)amino]ethyl]amino]methyl]-4-hydroxyphenyl)propanoic acid
(VI)828549-1-a1366302-52-4N-[[(1S)-1-Carboxy-5-([6-[3-(3-[[[2-[[[5-(2-carboxyethyl)-2-hydroxyphenyl]methyl](carboxymethyl)amino]ethyl](carboxymethyl)amino]methyl]-4-hydroxyphenyl)propanamido]hexanoyl]amino)pentyl]carbamoyl]-L-glutamic acid
OptimisedRoute 2Steps 4 · Total yield /
(V)828549-1-a,(V)828549-1-b1309876-75-2(VII)828549-1-b501-97-3(VIII)828549-1-b5657-17-0(IX) 828549-1-b143557-99-7(X)828549-1-b—(XI)828549-1-b—API · TLX-591 companion diagnostic (Telix Pharmaceuticals)
CodeCAS No.Intermediate
(V)828549-1-a,(V)828549-1-b1309876-75-23-(3-[[(Carboxymethyl)[2-[(carboxymethyl)([2-hydroxy-5-[3-oxo-3-(2,3,5,6-tetrafluorophenoxy)propyl]phenyl]methyl)amino]ethyl]amino]methyl]-4-hydroxyphenyl)propanoic acid
(VII)828549-1-b501-97-33-(4-Hydroxyphenyl)propionic acid
(VIII)828549-1-b5657-17-02,2'-(Ethane-1,2-diyldiazanediyl)diacetic acid
(IX) 828549-1-b143557-99-73,3'-(Ethane-1,2-diylbis[[(carboxymethyl)azanediyl]methylene(4-hydroxy-3,1-phenylene)])dipropanoic acid
(X)828549-1-b-2,2'-[Ethane-1,2-diylbis([[5-(2-carboxyethyl)-2-oxidophenyl]methyl]azanediyl)]diacetate iron(3+)
(XI)828549-1-b-[[2-[[[5-(2-Carboxyethyl)-2-oxidophenyl]methyl](carboxylatomethyl)amino]ethyl]([2-oxido-5-[3-oxo-3-(2,3,5,6-tetrafluorophenoxy)propyl]phenyl]methyl)amino]acetate iron(3+)

Frequently asked questions

What are the approved indications of TLX-591 companion diagnostic (Telix Pharmaceuticals)?

Approved indications include: Prostate cancer, Diagnostic agent.

When does the TLX-591 companion diagnostic (Telix Pharmaceuticals) patent expire?

No public expiry year is available for TLX-591 companion diagnostic (Telix Pharmaceuticals) yet; this page updates once verified.

How many synthesis routes are recorded for TLX-591 companion diagnostic (Telix Pharmaceuticals)?

2 synthesis routes are recorded; the shortest is 4 steps with / total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy TLX-591 companion diagnostic (Telix Pharmaceuticals) intermediates?

All intermediates in TLX-591 companion diagnostic (Telix Pharmaceuticals) routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for TLX-591 companion diagnostic (Telix Pharmaceuticals) intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-27